SCHEMBL17832298

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24427332	0.80	TLR9 (0.42)	KDM4ESMN1; SMN2HPGDALDH1A1NPC1
	SCHEMBL24427598	0.78	KDM4E (0.42)	KDM4ESMN1; SMN2HPGDMAPK14GCGR
	SCHEMBL24427244	0.75	MPL (0.40)	SMN1; SMN2ACHEPARP1
	SCHEMBL24427514	0.74	PDPK1 (0.52)	—
	SCHEMBL24427480	0.73	MAPK14 (0.36)	MAPK14ALOX5
	SCHEMBL24428023	0.72	CREBBP (0.37)	KDM4EHPGDALDH1A1MAPTPOLB
	SCHEMBL24427251	0.72	MAPK14 (0.39)	KDM4ESMN1; SMN2HPGDMAPK14ALDH1A1
	SCHEMBL17832296	0.71	NOS3 (0.34)	KDM4ESMN1; SMN2HPGDPOLBADORA2A
	SCHEMBL24427894	0.70	RPS6KA3 (0.49)	KDM4ESMN1; SMN2HPGDMAPK14GCGR
	SCHEMBL24427783	0.70	KDM4E (0.35)	KDM4ESMN1; SMN2HPGDPOLBPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.