Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 11/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.31 |
| ▸ | USP1 | O94782 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17824432 | 0.92 | CNR2 (0.35) | CA12CA9CA1CA2PTGS2 | |
| SCHEMBL17824483 | 0.88 | KCNH2 (0.33) | CA12CA9CA1CA2PTGS2 | |
| SCHEMBL22190266 | 0.85 | KCNH2 (0.34) | CA12CA9CA1CA2KCNH2 | |
| SCHEMBL17832754 | 0.84 | KCNH2 (0.35) | CA12CA9CA1CA2KCNH2 | |
| SCHEMBL17494868 | 0.84 | DDR1 (0.37) | CA12CA9CA1CA2PTGS2 | |
| SCHEMBL30958299 | 0.84 | DDR1 (0.37) | CA12CA9CA1CA2PTGS2 | |
| SCHEMBL17824513 | 0.84 | CA12 (0.36) | CA12CA9CA1CA2PTGS2 | |
| SCHEMBL17832777 | 0.84 | CA12 (0.34) | CA12CA9CA1CA2PTGS2 | |
| SCHEMBL19678796 | 0.84 | CNR2 (0.33) | CA12CA9CA1CA2PTGS2 | |
| SCHEMBL21869852 | 0.83 | CNR2 (0.32) | CA12CA9CA1CA2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230284-B1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-04-15 | — | — | EP | disclosed |
| EP-3230284-B1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-04-15 | — | — | EP | disclosed |
| US-20170349581-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATION AG (CH) | 2017-12-07 | — | — | US | disclosed |
| US-20170349581-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATION AG (CH) | 2017-12-07 | — | — | US | disclosed |
| WO-2016091731-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349581-A1 | PESTICIDALLY ACTIVE TETRACYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | DDT, TST, ACHE | CA12 3990/4885CA9 3012/4885CA1 1052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.