Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17832914 | 0.89 | LTA4H (0.42) | LTA4HAPPLMNASLC6A6CYP2C19 | |
| SCHEMBL18251504 | 0.83 | LTA4H (0.41) | LTA4HAPP | |
| SCHEMBL18251201 | 0.79 | LTA4H (0.39) | LTA4HAPP | |
| SCHEMBL16790489 | 0.79 | LTA4H (0.39) | LTA4HAPPLMNA | |
| SCHEMBL17771977 | 0.79 | APP (0.60) | LTA4HAPPLMNASLC6A6CYP2C19 | |
| SCHEMBL17787477 | 0.79 | APP (0.54) | LTA4HAPPLMNASLC6A6CYP2C19 | |
| SCHEMBL19704691 | 0.77 | LTA4H (0.38) | LTA4H | |
| SCHEMBL31295636 | 0.77 | APP (0.58) | LTA4HAPPLMNASLC6A6CYP2C19 | |
| SCHEMBL25199783 | 0.76 | APP (0.39) | LTA4HAPPLMNASLC6A6CYP2C19 | |
| SCHEMBL5335869 | 0.76 | KDM4C (0.40) | LTA4HAPPLMNASLC6A6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094509-A1 | BCL XL INHIBITORY COMPOUNDS HAVING LOW CELL PERMEABILITY AND ANTIBODY DRUG CONJUGATES INCLUDING THE SAME | ABBVIE INC. (US) | 2016-06-16 | — | — | WO | disclosed |