Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | AKT1 | P31749 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | PRKCH | P24723 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17817441 | 0.90 | LMNA (0.56) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL1654879 | 0.86 | SMN1; SMN2 (0.42) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL17833014 | 0.84 | LMNA (0.58) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL13619237 | 0.84 | LMNA (0.58) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL23016765 | 0.83 | LMNA (0.68) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL19089460 | 0.83 | LMNA (0.68) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL18970789 | 0.83 | LMNA (0.68) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL19089198 | 0.83 | LMNA (0.68) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL26032527 | 0.83 | BBOX1 (0.47) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL17817502 | 0.80 | CYP3A4 (0.57) | LMNAAKT1ESR1ADORA3CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094226-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | GLYCOREGIMMUNE, INC. (US) | 2016-06-16 | — | — | WO | disclosed |