SCHEMBL17833005

SCHEMBL17833005

CCCCCCCCCCCCCCCCO[C@@H]1CO[C@H]2C1OC[C@H]2OCCC

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
TDP1 Q9NUW8 1/20 0.46
GBA1 P04062 3/20 0.42
BCHE P06276 3/20 0.41
RECQL P46063 2/20 0.36
GLA P06280 1/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
EPHX2 P34913 1/20 0.36
BLM P54132 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PPP5C P53041 1/20 0.36
SPHK2 Q9NRA0 1/20 0.36
SPHK1 Q9NYA1 1/20 0.36
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17817171 1.00 ALDH1A1 (0.46) ALDH1A1TDP1GBA1BCHERECQL
SCHEMBL18118482 0.96 ALDH1A1 (0.48) ALDH1A1TDP1GBA1BCHESMN1; SMN2
SCHEMBL21159682 0.88 BCHE (0.43) ALDH1A1TDP1BCHESMN1; SMN2PPP5C
SCHEMBL18118484 0.88 ALDH1A1 (0.42) ALDH1A1TDP1GBA1BCHERECQL
SCHEMBL18118485 0.88 ALDH1A1 (0.42) ALDH1A1TDP1GBA1BCHERECQL
SCHEMBL18118480 0.86 GBA1 (0.49) ALDH1A1TDP1GBA1BCHEPPP5C
SCHEMBL1896686 0.86 GBA1 (0.49) ALDH1A1TDP1GBA1BCHEPPP5C
SCHEMBL18107973 0.86 GBA1 (0.49) ALDH1A1TDP1GBA1BCHEPPP5C
SCHEMBL18108272 0.86 GBA1 (0.49) ALDH1A1TDP1GBA1BCHEPPP5C
SCHEMBL18107969 0.86 GBA1 (0.49) ALDH1A1TDP1GBA1BCHEPPP5C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016094226-A1 PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS GLYCOREGIMMUNE, INC. (US) 2016-06-16 WO disclosed