Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UNG | P13051 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL3217475 | 0.88 | KMO (0.47) | CYP2C9CYP2D6HIF1AKMOCYP2C8 | |
| Isophthalic Acid SCHEMBL2289641 | 0.85 | KMO (0.50) | UNGCYP2C9CYP2D6HIF1AKMO | |
| Terephthalic Acid SCHEMBL3128260 | 0.85 | UNG (0.49) | UNGCYP2C9KMOMEN1KMT2A | |
| Terephthalic Acid SCHEMBL6440220 | 0.84 | LMNA (0.49) | UNGCYP2D6NPC1MAPTRAB9A | |
| Isophthalic Acid SCHEMBL5671924 | 0.82 | CA12 (0.52) | UNGCYP2C9KMOKIF11HPGD | |
| Isophthalic Acid SCHEMBL259040 | 0.82 | CA12 (0.52) | UNGCYP2C9KMOKIF11HPGD | |
| Isophthalic Acid SCHEMBL30479216 | 0.82 | CA12 (0.52) | UNGCYP2C9KMOKIF11HPGD | |
| Isophthalic Acid SCHEMBL5670699 | 0.82 | CA12 (0.52) | UNGCYP2C9KMOKIF11HPGD | |
| Isophthalic Acid SCHEMBL15571798 | 0.80 | KMO (0.49) | UNGCYP2C9CYP2D6HIF1AKMO | |
| Isophthalic Acid SCHEMBL15571507 | 0.80 | KMO (0.49) | UNGCYP2C9CYP2D6HIF1AKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110117341-A1 | MULTILAYERED FILM WITH EXCELLENT ANTIFOGGING PROPERTY | GUNZE LIMITED (JP) | 2011-05-19 | — | — | US | claimed |
| EP-2578398-B1 | MULTILAYER FILM AND PACKAGE BODY | SUMITOMO BAKELITE CO (JP) | 2016-03-30 | — | — | EP | disclosed |
| US-8551590-B2 | Multilayer film and packaging material | SUMITOMO BAKELITE CO., LTD (JP) | 2013-10-08 | — | — | US | disclosed |
| EP-2578398-A1 | MULTILAYER FILM AND PACKAGING MATERIAL | Sumitomo Bakelite Co., Ltd. (JP) | 2013-04-10 | — | — | EP | disclosed |
| US-20130065002-A1 | MULTILAYER FILM AND PACKAGING MATERIAL | SUMITOMO BAKELITE CO., LTD. (JP) | 2013-03-14 | — | — | US | disclosed |
| US-20110117341-A1 | MULTILAYERED FILM WITH EXCELLENT ANTIFOGGING PROPERTY | GUNZE LIMITED (JP) | 2011-05-19 | — | — | US | disclosed |