Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17829901 | 0.88 | KCNH2 (0.40) | PRKCIS1PR1S1PR3CHEK1KCNH2 | |
| SCHEMBL17833279 | 0.86 | CTNNB1 (0.37) | PRKCIS1PR1S1PR3KCNH2CTSK | |
| SCHEMBL17833281 | 0.82 | SYK (0.38) | PRKCIS1PR1S1PR3CHEK1KCNH2 | |
| SCHEMBL17833286 | 0.81 | SYK (0.38) | PRKCIS1PR1S1PR3RIPK1KCNH2 | |
| SCHEMBL17833143 | 0.81 | PRKCI (0.34) | PRKCIS1PR1S1PR3RIPK1STK17A | |
| SCHEMBL17833282 | 0.80 | SYK (0.39) | PRKCIS1PR1S1PR3KCNH2CTSK | |
| SCHEMBL17833283 | 0.78 | SYK (0.40) | KCNH2CTSK | |
| SCHEMBL17833161 | 0.77 | KMT2A (0.40) | KCNH2CTSKNOS3NOS1 | |
| SCHEMBL17829946 | 0.77 | SYK (0.47) | STK17A | |
| SCHEMBL17829899 | 0.76 | SYK (0.36) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094730-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | SYNERECA PHARMACEUTICALS, INC. (US) | 2016-06-16 | — | — | WO | disclosed |