Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | USP1 | O94782 | 1/20 | 0.35 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.35 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17833286 | 0.93 | SYK (0.38) | SYKKDM4EALDH1A1GAAKCNH2 | |
| SCHEMBL17833282 | 0.92 | SYK (0.39) | SYKCYP1A2CYP3A4CYP2C19KDM4E | |
| SCHEMBL17833279 | 0.92 | CTNNB1 (0.37) | SYKKDM4EALDH1A1GAAKCNH2 | |
| SCHEMBL17833152 | 0.89 | ACP1 (0.42) | SYKCYP1A2CYP3A4USP2CYP2C19 | |
| SCHEMBL17829870 | 0.88 | ALDH1A1 (0.47) | SYKALDH1A1KCNH2RAD52KMT2A | |
| SCHEMBL17833143 | 0.85 | PRKCI (0.34) | SYKKCNH2CTSKS1PR1S1PR3 | |
| SCHEMBL17833283 | 0.85 | SYK (0.40) | SYKCYP1A2CYP3A4CYP2C19KDM4E | |
| SCHEMBL17833150 | 0.83 | CYP1A2 (0.41) | CYP1A2CYP3A4USP2CYP2C19CLK4 | |
| SCHEMBL17833161 | 0.83 | KMT2A (0.40) | SYKKDM4EALDH1A1GAAKCNH2 | |
| SCHEMBL17829946 | 0.82 | SYK (0.47) | SYKKDM4EALDH1A1GAAHMOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094730-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | SYNERECA PHARMACEUTICALS, INC. (US) | 2016-06-16 | — | — | WO | disclosed |