Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17833189 | 0.92 | KMT2A (0.39) | RAD52KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17829800 | 0.87 | RAD52 (0.58) | RAD52KMT2AACP1SYKPOLB | |
| SCHEMBL17833192 | 0.85 | PRKCI (0.40) | RAD52KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17829568 | 0.84 | RAD52 (0.59) | RAD52KMT2AACP1SYKPOLB | |
| SCHEMBL17829683 | 0.82 | KDM1A (0.40) | RAD52KMT2ASYKROCK2ROCK1 | |
| SCHEMBL17833283 | 0.80 | SYK (0.40) | RAD52KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17829798 | 0.79 | POLB (0.53) | RAD52KMT2ASYKPOLBALDH1A1 | |
| SCHEMBL17829910 | 0.79 | SYK (0.44) | RAD52KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17833237 | 0.79 | KMT2A (0.39) | RAD52KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17833278 | 0.78 | CYP11B2 (0.38) | RAD52KMT2ACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094730-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | SYNERECA PHARMACEUTICALS, INC. (US) | 2016-06-16 | — | — | WO | disclosed |