Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 7/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 2/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17833229 | 0.89 | RAD52 (0.50) | KDM1ATGFBR1MAPK14KMT2AKDM4E | |
| SCHEMBL17833191 | 0.82 | RAD52 (0.42) | KMT2AKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL17833189 | 0.80 | KMT2A (0.39) | KMT2AKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL17833192 | 0.76 | PRKCI (0.40) | KMT2AKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL17833283 | 0.75 | SYK (0.40) | KMT2AKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL17829910 | 0.74 | SYK (0.44) | KMT2AKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL17833237 | 0.74 | KMT2A (0.39) | KMT2AKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL17833278 | 0.74 | CYP11B2 (0.38) | KMT2AKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL17833161 | 0.73 | KMT2A (0.40) | KMT2AKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL17833238 | 0.73 | TNKS (0.41) | KDM1AKMT2AKDM4EALDH1A1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160168140-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | SYNERECA PHARMACEUTICALS (US) | 2016-06-16 | — | — | US | disclosed |
| US-20160168140-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | SYNERECA PHARMACEUTICALS (US) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168140-A1 | HETEROCYCLIC COMPOUNDS AS ANTIBIOTIC POTENTIATORS | FOS, FOSB, YAP1 | KDM1A 4599/4885TGFBR1 3916/4885MAPK14 266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.