Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320191 | 0.82 | NPC1 (0.67) | HIF1ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL17833243 | 0.81 | MEN1 (0.49) | HIF1AFAAHNPC1RAB9AMEN1 | |
| SCHEMBL13188439 | 0.77 | IKBKB (0.67) | IKBKBMEN1KMT2ARXFP1ALDH1A1 | |
| SCHEMBL13073425 | 0.77 | HDAC2 (0.76) | HIF1ANPC1RAB9AMEN1KMT2A | |
| SCHEMBL25782291 | 0.76 | ALOX15 (0.71) | IKBKBNPC1RAB9AMEN1KMT2A | |
| SCHEMBL15606117 | 0.75 | HDAC1 (0.54) | IKBKBALDH1A1HPGDHDAC1KDM4E | |
| SCHEMBL15562157 | 0.75 | KLKB1 (0.61) | IKBKBHDAC1 | |
| SCHEMBL18632331 | 0.74 | ROCK2 (0.53) | IKBKBMEN1KMT2AROCK2ROCK1 | |
| SCHEMBL10133038 | 0.74 | MEN1 (0.72) | HIF1ANPC1RAB9AMEN1KMT2A | |
| SCHEMBL8339590 | 0.74 | MAPT (0.63) | HIF1AFAAHNPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11185100-B2 | Methods for modulating taste receptors | MARS, INCORPORATED (US) | 2021-11-30 | — | — | US | disclosed |
| EP-3229610-B1 | FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME | MARS INC (US) | 2021-06-09 | — | — | EP | disclosed |
| US-20190021380-A1 | FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME | MARS, INCORPORATED (US) | 2019-01-24 | — | — | US | disclosed |
| US-20180168208-A1 | FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME | MARS, INCORPORATED (US) | 2018-06-21 | — | — | US | disclosed |
| WO-2016094702-A2 | METHODS FOR MODULATING TASTE RECEPTORS | MARS, INCORPORATED (US) | 2016-06-16 | — | — | WO | disclosed |