Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RRM1 | P23921 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24397093 | 0.75 | NPC1 (0.44) | NPC1RAB9ACDC25BMEN1KMT2A | |
| SCHEMBL24397521 | 0.73 | NPC1 (0.43) | NPC1RAB9AMEN1KMT2AESR1 | |
| SCHEMBL10710348 | 0.71 | NPC1 (0.50) | NPC1RAB9ACDC25BMEN1KMT2A | |
| SCHEMBL24397015 | 0.69 | CNR2 (0.39) | NPC1RAB9ACDC25BKMT2AALDH1A1 | |
| SCHEMBL17833903 | 0.69 | KCNA5 (0.36) | NPC1RAB9ACDC25BALDH1A1KDM4E | |
| SCHEMBL18648019 | 0.69 | CNR1 (0.42) | NPC1RAB9AMEN1KMT2AGAA | |
| SCHEMBL6127765 | 0.69 | CNR1 (0.42) | NPC1RAB9AMEN1KMT2AGAA | |
| SCHEMBL13656524 | 0.67 | KMT2A (0.41) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL17834977 | 0.67 | MEN1 (0.38) | RAB9AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL17184098 | 0.67 | ALDH1A1 (0.43) | NPC1RAB9AMEN1KMT2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9746771-B2 | Laminate body | FUJIFILM CORPORATION (JP) | 2017-08-29 | — | — | US | disclosed |
| US-9746771-B2 | Laminate body | FUJIFILM CORPORATION (JP) | 2017-08-29 | — | — | US | disclosed |
| US-20160170303-A1 | LAMINATE BODY | FUJIFILM CORPORATION (JP) | 2016-06-16 | — | — | US | disclosed |
| US-20160170303-A1 | LAMINATE BODY | FUJIFILM CORPORATION (JP) | 2016-06-16 | — | — | US | disclosed |