Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17834020 | 0.89 | RAB9A (0.46) | TRPV1MAPTALDH1A1MAPK1RAB9A | |
| SCHEMBL17978436 | 0.81 | KMT2A (0.50) | TRPV1S1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL17825433 | 0.77 | CYP19A1 (0.48) | MAPTALDH1A1 | |
| SCHEMBL17834025 | 0.76 | CYP19A1 (0.44) | MAPTALDH1A1MAPK1RAB9ANPC1 | |
| SCHEMBL4407024 | 0.76 | KMT2A (0.41) | TRPV1ALDH1A1 | |
| SCHEMBL22533617 | 0.75 | RAB9A (0.48) | TRPV1S1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL4413426 | 0.74 | KMT2A (0.42) | TRPV1MAPTALDH1A1MAPK1RAB9A | |
| SCHEMBL24794605 | 0.74 | TRPV1 (0.52) | TRPV1S1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL17834016 | 0.73 | RAB9A (0.48) | MAPK1RAB9ANPC1 | |
| SCHEMBL4404394 | 0.73 | TRPV1 (0.56) | TRPV1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016091228-A1 | SUBSTITUTED PHENYLTETRAZOLE, ITS USE AND PHARMACEUTICAL PREPARATION CONTAINING IT | UNIVERZITA KARLOVA V PRAZE (CZ) | 2016-06-16 | — | — | WO | disclosed |