Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | GRK5 | P34947 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2651131 | 0.84 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL29678264 | 0.84 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL1674287 | 0.83 | XDH (0.49) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL17834020 | 0.81 | RAB9A (0.46) | CYP19A1L3MBTL1CHEK1DAPK3GRK5 | |
| SCHEMBL17834015 | 0.77 | TRPV1 (0.49) | ALDH1A1MAPT | |
| SCHEMBL17834025 | 0.76 | CYP19A1 (0.44) | CYP19A1L3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL5255709 | 0.76 | MAPT (0.57) | ALDH1A1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL17834021 | 0.73 | KMT2A (0.58) | L3MBTL1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL17825313 | 0.73 | RAB9A (0.54) | L3MBTL1ALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL926428 | 0.73 | ALDH1A1 (0.52) | CHEK1DAPK3GRK5LIMK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016091228-A1 | SUBSTITUTED PHENYLTETRAZOLE, ITS USE AND PHARMACEUTICAL PREPARATION CONTAINING IT | UNIVERZITA KARLOVA V PRAZE (CZ) | 2016-06-16 | — | — | WO | disclosed |
| WO-2016091228-A1 | SUBSTITUTED PHENYLTETRAZOLE, ITS USE AND PHARMACEUTICAL PREPARATION CONTAINING IT | UNIVERZITA KARLOVA V PRAZE (CZ) | 2016-06-16 | — | — | WO | disclosed |