Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 8/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17367790 | 0.87 | CYP2A6 (0.62) | CYP11B2CYP11B1CYP19A1EPHX2PRMT6 | |
| SCHEMBL29353429 | 0.87 | CYP2A6 (0.62) | CYP11B2CYP11B1CYP19A1EPHX2PRMT6 | |
| SCHEMBL16410013 | 0.87 | CYP2A6 (0.62) | CYP11B2CYP11B1CYP19A1EPHX2PRMT6 | |
| SCHEMBL29993469 | 0.87 | CYP2A6 (0.62) | CYP11B2CYP11B1CYP19A1EPHX2PRMT6 | |
| SCHEMBL30435038 | 0.87 | CYP2A6 (0.62) | CYP11B2CYP11B1CYP19A1EPHX2PRMT6 | |
| SCHEMBL17834290 | 0.84 | PRMT6 (0.45) | CYP11B2CYP11B1CYP19A1PRMT6CYP3A4 | |
| SCHEMBL18325327 | 0.82 | CYP2A6 (0.52) | CYP11B2CYP11B1CYP19A1EPHX2PRMT6 | |
| SCHEMBL19238737 | 0.82 | CYP19A1 (0.58) | CYP11B2CYP11B1CYP19A1MEN1PSIP1 | |
| SCHEMBL18327328 | 0.82 | CYP19A1 (0.58) | CYP11B2CYP11B1CYP19A1MEN1PSIP1 | |
| SCHEMBL17755349 | 0.82 | CYP19A1 (0.58) | CYP11B2CYP11B1CYP19A1MEN1PSIP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016091887-A2 | AMBIPOLAR HOST MATERIALS AND USE THEREOF | CYNORA GMBH (DE) | 2016-06-16 | — | — | WO | disclosed |