Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | PRKCI | P41743 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22376564 | 0.94 | SMN1; SMN2 (0.44) | PRMT6PRKCIKIF11NOTUMPDE4B | |
| SCHEMBL26083938 | 0.88 | PDE4B (0.44) | PDE4BPDE4D | |
| SCHEMBL23775951 | 0.86 | L3MBTL1 (0.47) | PDE4BPDE4D | |
| SCHEMBL19274949 | 0.86 | NOTUM (0.54) | PRMT6PRKCIKIF11NOTUMMAPK14 | |
| SCHEMBL19270247 | 0.86 | NOTUM (0.54) | PRMT6PRKCIKIF11NOTUMMAPK14 | |
| SCHEMBL17834294 | 0.84 | CYP11B2 (0.48) | PRMT6DHFRCYP17A1S1PR1CYP3A4 | |
| SCHEMBL17467256 | 0.83 | PDE4B (0.43) | PDE4BPDE4D | |
| SCHEMBL18327489 | 0.82 | NOTUM (0.62) | PRMT6PRKCIKIF11NOTUMMAPK14 | |
| SCHEMBL19270246 | 0.82 | NOTUM (0.62) | PRMT6PRKCIKIF11NOTUMMAPK14 | |
| SCHEMBL17343253 | 0.82 | NOTUM (0.50) | PRMT6PRKCIKIF11NOTUMMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016091887-A2 | AMBIPOLAR HOST MATERIALS AND USE THEREOF | CYNORA GMBH (DE) | 2016-06-16 | — | — | WO | disclosed |