Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 5/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 5/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | TPH1 | P17752 | 2/20 | 0.45 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15037029 | 0.94 | ITGB1 (0.53) | ITGB1ITGA4ITGB3ITGA2BACACB | |
| SCHEMBL15037102 | 0.94 | ITGB1 (0.53) | ITGB1ITGA4ITGB3ITGA2BACACB | |
| SCHEMBL15091874 | 0.94 | ITGB1 (0.53) | ITGB1ITGA4ITGB3ITGA2BACACB | |
| SCHEMBL15019772 | 0.94 | ITGB1 (0.53) | ITGB1ITGA4ITGB3ITGA2BACACB | |
| SCHEMBL15037257 | 0.88 | PPARG (0.51) | ITGB1ITGA4ITGB3ITGA2BACACB | |
| SCHEMBL22449060 | 0.88 | PPARG (0.51) | ITGB1ITGA4ITGB3ITGA2BACACB | |
| SCHEMBL15019925 | 0.86 | RAB9A (0.48) | ITGB1ITGA4ITGB3ITGA2BACACB | |
| SCHEMBL15019927 | 0.86 | RAB9A (0.48) | ITGB1ITGA4ITGB3ITGA2BACACB | |
| SCHEMBL15037027 | 0.86 | RAB9A (0.48) | ITGB1ITGA4ITGB3ITGA2BACACB | |
| SCHEMBL15091930 | 0.86 | RAB9A (0.48) | ITGB1ITGA4ITGB3ITGA2BACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094729-A1 | GLP-1 RECEPTOR MODULATORS | CELGENE INTERNATIONAL II SARL (CH) | 2016-06-16 | — | — | WO | disclosed |