Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9279565 | 0.86 | TSHR (0.41) | TSHRHTR2AHTR2CHTR2BMAPK1 | |
| SCHEMBL11075638 | 0.81 | SMN1; SMN2 (0.47) | TSHRMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL11625901 | 0.81 | TSHR (0.51) | TSHRHTR2AHTR2CHTR2BGRM1 | |
| SCHEMBL508943 | 0.81 | TDP1 (0.42) | TSHRHTR2BGRM1MEN1CYP1A2 | |
| SCHEMBL508992 | 0.80 | TSHR (0.50) | TSHRHTR2AHTR2CHTR2BGRM1 | |
| SCHEMBL10745903 | 0.80 | TSHR (0.54) | TSHRHTR2AHTR2CHTR2BGRM1 | |
| SCHEMBL654108 | 0.80 | TSHR (0.50) | TSHRHTR2AHTR2CHTR2BGRM1 | |
| SCHEMBL3138636 | 0.79 | TSHR (0.49) | TSHRHTR2AHTR2CHTR2BGRM1 | |
| SCHEMBL12737359 | 0.79 | GRM1 (0.65) | TSHRHTR2AHTR2CHTR2BGRM1 | |
| SCHEMBL14774822 | 0.77 | TSHR (0.51) | TSHRHTR2AHTR2CHTR2BGRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118118-A1 | HERBICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | BAYER CROPSCIENCE AG (DE) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118118-A1 | HERBICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES | PNPO, PDXK, PRDX1 | TSHR 2207/4885HTR2A 1252/4885HTR2C 1350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.