Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIFC1 | Q9BW19 | 11/20 | 0.60 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17968913 | 0.92 | KIFC1 (0.49) | KIFC1MCL1ITGB1ITGA4ITGB7 | |
| SCHEMBL15036992 | 0.92 | KIFC1 (0.49) | KIFC1MCL1ITGB1ITGA4ITGB7 | |
| SCHEMBL17834526 | 0.92 | KIFC1 (0.49) | KIFC1MCL1ITGB1ITGA4ITGB7 | |
| SCHEMBL17995223 | 0.92 | KIFC1 (0.52) | KIFC1GPR34MCL1ITGB1ITGA4 | |
| SCHEMBL22384495 | 0.90 | KIFC1 (0.50) | KIFC1GPR34MCL1ITGB1ITGA4 | |
| SCHEMBL22449054 | 0.89 | KIFC1 (0.48) | KIFC1MCL1ITGB1ITGA4ITGB7 | |
| SCHEMBL15037327 | 0.89 | KIFC1 (0.48) | KIFC1MCL1ITGB1ITGA4ITGB7 | |
| SCHEMBL15037392 | 0.88 | KIFC1 (0.43) | KIFC1MCL1ITGB1ITGA4ITGB7 | |
| SCHEMBL17968745 | 0.88 | KIFC1 (0.43) | KIFC1MCL1ITGB1ITGA4ITGB7 | |
| SCHEMBL17834867 | 0.88 | KIFC1 (0.43) | KIFC1MCL1ITGB1ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |
| US-10034886-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2018-07-31 | — | — | US | disclosed |
| US-10034886-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2018-07-31 | — | — | US | disclosed |
| US-20180021346-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2018-01-25 | — | — | US | disclosed |
| US-9795613-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2017-10-24 | — | — | US | disclosed |
| US-9795613-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2017-10-24 | — | — | US | disclosed |
| US-20160228450-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2016-08-11 | — | — | US | disclosed |
| WO-2016094729-A1 | GLP-1 RECEPTOR MODULATORS | CELGENE INTERNATIONAL II SARL (CH) | 2016-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160228450-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | KIFC1 4738/4885GPR34 115/4885MCL1 2102/4885 |
| US-20180021346-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | KIFC1 4738/4885GPR34 115/4885MCL1 2102/4885 |
| US-10034886-B2 | GLP-1 receptor modulators | GLP1R, GIPR, GCGR | KIFC1 4749/4885GPR34 132/4885MCL1 1664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.