Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIFC1 | Q9BW19 | 12/20 | 0.50 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 4/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17995223 | 0.91 | KIFC1 (0.52) | KIFC1GPR34MCL1ITGB1ITGA4 | |
| SCHEMBL17834856 | 0.90 | KIFC1 (0.60) | KIFC1GPR34MCL1ITGB1ITGA4 | |
| SCHEMBL16306244 | 0.83 | KIFC1 (0.42) | KIFC1MCL1MME | |
| SCHEMBL17834785 | 0.83 | KIFC1 (0.42) | KIFC1MCL1MME | |
| SCHEMBL15036992 | 0.83 | KIFC1 (0.49) | KIFC1MCL1ITGB1ITGA4ITGB7 | |
| SCHEMBL17834526 | 0.83 | KIFC1 (0.49) | KIFC1MCL1ITGB1ITGA4ITGB7 | |
| SCHEMBL17968913 | 0.83 | KIFC1 (0.49) | KIFC1MCL1ITGB1ITGA4ITGB7 | |
| SCHEMBL17834845 | 0.82 | KIFC1 (0.41) | KIFC1GPR34MME | |
| SCHEMBL17834777 | 0.81 | KIFC1 (0.45) | KIFC1MCL1ITGB1ITGA4ITGB7 | |
| SCHEMBL19485619 | 0.81 | KIFC1 (0.41) | KIFC1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |