SCHEMBL1783486

SCHEMBL1783486

C1=CNCCCNCCNCCCN1

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 9/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
ALDH1A1 P00352 1/20 0.41
HIF1A Q16665 1/20 0.40
MAPT P10636 1/20 0.40
PDE4A P27815 1/20 0.40
KDR P35968 1/20 0.40
MEN1 O00255 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM1 P11229 1/20 0.32
ADRA2C P18825 1/20 0.32
CCR2 P41597 1/20 0.32
CXCL12 P48061 1/20 0.32
BLM P54132 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1831026 0.86
SCHEMBL1781839 0.82 HIF1A (0.50) CXCR4SMN1; SMN2ALDH1A1HIF1AMAPT
SCHEMBL1780932 0.82
SCHEMBL1782105 0.82 HIF1A (0.50) CXCR4SMN1; SMN2ALDH1A1HIF1AMAPT
Piperazine SCHEMBL1091869 0.82 HIF1A (0.50) CXCR4SMN1; SMN2ALDH1A1HIF1AMAPT
SCHEMBL1783483 0.80 CXCR4 (0.60) CXCR4SMN1; SMN2ALDH1A1HIF1AMAPT
SCHEMBL577659 0.78 CXCR4 (1.00) CXCR4SMN1; SMN2ALDH1A1HIF1AMAPT
SCHEMBL576838 0.78 CXCR4 (1.00) CXCR4SMN1; SMN2ALDH1A1HIF1AMAPT
SCHEMBL3998680 0.78 CXCR4 (1.00) CXCR4SMN1; SMN2ALDH1A1HIF1AMAPT
SCHEMBL8503965 0.78 CXCR4 (1.00) CXCR4SMN1; SMN2ALDH1A1HIF1AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11332416-B2 Process for synthesizing fluorinated cyclic aliphatic compounds Westfälische Wilhelms-Universität Münster (DE) 2022-05-17 US disclosed
EP-3601203-B1 PROCESS FOR SYNTHESIZING FLUORINATED CYCLIC ALIPHATIC COMPOUNDS UNIV MUENSTER WESTFAELISCHE WILHELMS (DE) 2021-04-07 EP disclosed
US-10581001-B2 Organic electronic component having a charge carrier generation layer and the use of a zinc complex as a P-type dopant in charge carrier generation layers OSRAM OLED GMBH (DE) 2020-03-03 US disclosed
US-10411197-B2 Main group metal complexes as P-dopants for organic electronic matrix materials SIEMENS AKTIENGESELLSCHAFT (DE) 2019-09-10 US disclosed
US-10305047-B2 Main group metal complexes as p-dopants for organic electronic matrix materials SIEMENS AKTIENGESELLSCHAFT (DE) 2019-05-28 US disclosed
US-10256422-B2 Organic electronic component, use of a zinc complex as a p-dopant for organic electronic matrix materials OSRAM OLED GMBH (DE) 2019-04-09 US disclosed
EP-3246960-B1 MAIN GROUP METAL COMPLEXES AS P-DOPANTS FOR ORGANIC ELECTRONIC MATRIX MATERIALS SIEMENS AG (DE) 2018-10-24 EP disclosed
EP-2845240-B9 METAL COMPLEXES AS P-TYPE DOPANTS FOR ORGANIC ELECTRONIC MATRIX MATERIALS SIEMENS AG (DE) 2018-10-24 EP disclosed
US-20180277778-A1 ORGANIC ELECTRONIC COMPONENT HAVING A CHARGE CARRIER GENERATION LAYER AND THE USE OF A ZINC COMPLEX AS A P-TYPE DOPANT IN CHARGE CARRIER GENERATION LAYERS OSRAM OLED GMBH (DE) 2018-09-27 US disclosed
US-9954147-B2 Optoelectronic device, use of a dual emitter as wavelength conversion material OSRAM OLED GMBH (DE) 2018-04-24 US disclosed
US-6432900-B1 ANTISOILANTS UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-08-13 US disclosed
US-20020049148-A1 Bleach catalyst and composition and method for bleaching a substrate UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-04-25 US disclosed
US-20020023303-A1 Method for reducing dye fading of fabrics in laundry bleaching compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-02-28 US disclosed
US-20020013246-A1 Composition and method for bleaching laundry fabrics UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-01-31 US disclosed
US-20020010120-A1 Composition and method for bleaching a substrate UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-01-24 US disclosed
US-20020010121-A1 Bleaching and dye transfer inhibiting composition and method for laundry fabrics UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-01-24 US disclosed
US-6340661-B1 FOR BLEACHING FABRIC STAINS WITHOUT UNACCEPTABLE TRANSFER OF DYES BETWEEN FABRICS UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-01-22 US disclosed
US-20010025019-A1 Bleaching composition UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2001-09-27 US disclosed
US-20010009271-A1 Bleaching composition UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2001-07-26 US disclosed
WO-2001048138-A2 BLEACHING COMPOSITION UNILEVER N.V. (NL) 2001-07-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11332416-B2 Process for synthesizing fluorinated cyclic aliphatic compounds HRH4, HRH1, AHR CXCR4 1059/4885SMN1; SMN2 4460/4885ALDH1A1 2748/4885
US-10581001-B2 Organic electronic component having a charge carrier generation layer and the use of a zinc complex as a P-type dopant in charge carrier generation layers SCO2, NCOA4, NR4A2 CXCR4 394/4885SMN1; SMN2 2217/4885ALDH1A1 2367/4885
US-10305047-B2 Main group metal complexes as p-dopants for organic electronic matrix materials SCO2, SOD3, NCOA3 CXCR4 3361/4885SMN1; SMN2 1186/4885ALDH1A1 1949/4885
US-20180277778-A1 ORGANIC ELECTRONIC COMPONENT HAVING A CHARGE CARRIER GENERATION LAYER AND THE USE OF A ZINC COMPLEX AS A P-TYPE DOPANT IN CHARGE CARRIER GENERATION LAYERS SCO2, NCOA4, NR4A2 CXCR4 394/4885SMN1; SMN2 2217/4885ALDH1A1 2367/4885
US-10411197-B2 Main group metal complexes as P-dopants for organic electronic matrix materials SCO2, KMO, NOXO1 CXCR4 1914/4885SMN1; SMN2 1418/4885ALDH1A1 2235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.