Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIFC1 | Q9BW19 | 6/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.40 |
| ▸ | FEN1 | P39748 | 5/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | MTTP | P55157 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17834937 | 0.94 | KIFC1 (0.37) | KIFC1ALOX5APFEN1S1PR5PYGL | |
| SCHEMBL17834794 | 0.93 | S1PR1 (0.39) | KIFC1ALOX5APFEN1S1PR5PYGL | |
| SCHEMBL17995149 | 0.93 | S1PR1 (0.40) | S1PR5PYGLS1PR4S1PR1S1PR3 | |
| SCHEMBL17995193 | 0.91 | PYGL (0.37) | ALOX5APFEN1S1PR5CTSLPYGL | |
| SCHEMBL17995153 | 0.91 | CCR1 (0.39) | S1PR5PYGLS1PR4S1PR1S1PR3 | |
| SCHEMBL17834792 | 0.90 | PSMB5 (0.35) | S1PR5PYGLS1PR4S1PR1S1PR3 | |
| SCHEMBL17995228 | 0.90 | KDM1A (0.40) | S1PR5PYGLS1PR4S1PR1S1PR3 | |
| SCHEMBL17834662 | 0.86 | KIFC1 (0.37) | KIFC1S1PR5PYGLS1PR4S1PR1 | |
| SCHEMBL19485639 | 0.85 | ALOX5AP (0.39) | KIFC1ALOX5APFEN1S1PR5PYGL | |
| SCHEMBL17834425 | 0.85 | KIFC1 (0.38) | KIFC1ALOX5APFEN1S1PR5PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |
| US-10034886-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2018-07-31 | — | — | US | disclosed |
| US-20180021346-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2018-01-25 | — | — | US | disclosed |
| US-9795613-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2017-10-24 | — | — | US | disclosed |
| WO-2016094729-A1 | GLP-1 RECEPTOR MODULATORS | CELGENE INTERNATIONAL II SARL (CH) | 2016-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180021346-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | KIFC1 4738/4885ALOX5AP 3115/4885FEN1 3722/4885 |
| US-10034886-B2 | GLP-1 receptor modulators | GLP1R, GIPR, GCGR | KIFC1 4749/4885ALOX5AP 3438/4885FEN1 3634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.