Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.40 |
| ▸ | USP8 | P40818 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19754289 | 0.87 | PDK2 (0.38) | PDK2ALDH1A1EGLN1 | |
| SCHEMBL15084749 | 0.84 | CYP11B1 (0.41) | CYP11B1CYP11B2PDK2USP8MAPT | |
| SCHEMBL17835006 | 0.84 | CYP11B2 (0.44) | CYP11B1CYP11B2PDK2CYP19A1CYP17A1 | |
| SCHEMBL12126537 | 0.77 | PDK2 (0.42) | PDK2ALDH1A1CYP1A2CYP3A4TDP2 | |
| SCHEMBL17835066 | 0.76 | PDK2 (0.40) | PDK2NPC1RAB9AALDH1A1TDP2 | |
| SCHEMBL20689955 | 0.75 | ALDH1A1 (0.38) | NPC1RAB9AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL19007133 | 0.75 | PDK2 (0.43) | PDK2MAPTALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL29461269 | 0.75 | PDK2 (0.43) | PDK2MAPTALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL20689959 | 0.75 | HTT (0.38) | MAPTALDH1A1CYP1A2CYP3A4CYP2A6 | |
| SCHEMBL13085651 | 0.74 | EGLN1 (0.38) | PDK2NPC1RAB9AALDH1A1TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10683453-B2 | Organic compounds with soluble groups | MERCK PATENT GMBH (DE) | 2020-06-16 | — | — | US | disclosed |
| EP-3230403-B1 | ORGANIC COMPOUNDS WITH SOLUBLE GROUPS | MERCK PATENT GMBH (DE) | 2019-10-09 | — | — | EP | disclosed |
| US-20170369773-A1 | ORGANIC COMPOUNDS WITH SOLUBLE GROUPS | UDC IRELAND LIMITED (IE) | 2017-12-28 | — | — | US | disclosed |
| WO-2016091353-A1 | ORGANIC COMPOUNDS WITH SOLUBLE GROUPS | MERCK PATENT GMBH (DE) | 2016-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170369773-A1 | ORGANIC COMPOUNDS WITH SOLUBLE GROUPS | SLCO4C1, SLCO1B3, SLCO2B1 | CYP11B1 348/4885CYP11B2 228/4885PDK2 2619/4885 |
| US-10683453-B2 | Organic compounds with soluble groups | SLCO4C1, SLCO1B3, SLCO2B1 | CYP11B1 348/4885CYP11B2 228/4885PDK2 2619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.