Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27306641 | 0.85 | CTSK (0.36) | BRD4MAPK1 | |
| SCHEMBL15473897 | 0.72 | — | — | |
| SCHEMBL1075866 | 0.70 | KDM1A (0.38) | — | |
| SCHEMBL21737099 | 0.68 | — | — | |
| SCHEMBL30125635 | 0.68 | — | — | |
| SCHEMBL13349041 | 0.68 | — | — | |
| SCHEMBL27566686 | 0.68 | — | — | |
| SCHEMBL17260752 | 0.67 | BRD4 (0.37) | BRD4 | |
| SCHEMBL28186546 | 0.65 | PDE10A (0.37) | — | |
| SCHEMBL26729777 | 0.65 | TSHR (0.33) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160168170-A1 | PROCESS FOR THE PREPARATION OF HETEROCYCLIC ESTER DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168170-A1 | PROCESS FOR THE PREPARATION OF HETEROCYCLIC ESTER DERIVATIVES | FLT3, FES, FLT1 | BRD4 2063/4885RPS6KB1 159/4885MAPK1 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.