Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | SPNS2 | Q8IVW8 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17835018 | 0.85 | BRD4 (0.33) | MAPK1BRD4 | |
| SCHEMBL5527952 | 0.75 | RPS6KB1 (0.48) | CTSKCTSSCYP19A1PDE10AMAPT | |
| SCHEMBL13702951 | 0.72 | PDE10A (0.37) | SPNS2PDE10AMAPTKDM4EALDH1A1 | |
| SCHEMBL15033451 | 0.71 | PDE10A (0.35) | SPNS2PDE10ABRD4MAPTKDM4E | |
| SCHEMBL15473897 | 0.70 | — | — | |
| Bromide SCHEMBL16059581 | 0.69 | SPNS2 (0.33) | SPNS2PDE10AMAPTKDM4EALDH1A1 | |
| SCHEMBL28185774 | 0.68 | PDE10A (0.40) | PDE10AALDH1A1 | |
| SCHEMBL13384289 | 0.66 | NOS3 (0.33) | CTSKCTSSSPNS2MAPTKDM4E | |
| SCHEMBL12362482 | 0.64 | PDE10A (0.58) | PDE10A | |
| SCHEMBL17260752 | 0.64 | BRD4 (0.37) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1039323-C | Imidazopyriding derivatives and process for preparation thereof | TANABE SEIYAKU CO (JP) | 1998-07-29 | — | — | CN | disclosed |
| CN-1070912-A | Imidazopyridine derivatives and preparation method thereof | TANABE SEIYAKU CO (JP) | 1993-04-14 | — | — | CN | disclosed |