Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17835282 | 1.00 | CYP1A2 (0.46) | CYP1A2ATML3MBTL1 | |
| SCHEMBL17835273 | 1.00 | CYP1A2 (0.46) | CYP1A2ATML3MBTL1 | |
| SCHEMBL17835275 | 1.00 | CYP1A2 (0.46) | CYP1A2ATML3MBTL1 | |
| SCHEMBL17835267 | 1.00 | CYP1A2 (0.46) | CYP1A2ATML3MBTL1 | |
| SCHEMBL18323919 | 0.86 | — | — | |
| SCHEMBL21134596 | 0.85 | CYP1A2 (0.42) | CYP1A2 | |
| SCHEMBL17834072 | 0.79 | CYP1A2 (0.41) | CYP1A2 | |
| SCHEMBL17834078 | 0.79 | CYP1A2 (0.41) | CYP1A2 | |
| SCHEMBL17834104 | 0.79 | CYP1A2 (0.41) | CYP1A2 | |
| SCHEMBL17834105 | 0.79 | CYP1A2 (0.41) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160168090-A1 | NOVEL INDOLE DERIVATIVES AND THEIR USE IN NEURODEGENERATIVE DISEASES | MERCK PATENT GMBH (DE) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168090-A1 | NOVEL INDOLE DERIVATIVES AND THEIR USE IN NEURODEGENERATIVE DISEASES | P2RX3, P2RX7, P2RX2 | CYP1A2 1617/4885ATM 2968/4885L3MBTL1 4552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.