Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.47 |
| ▸ | ESR1 | P03372 | 4/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | ESRRG | P62508 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1373841 | 0.92 | CYP19A1 (0.50) | ARHPGDCYP19A1ALDH1A1PDE4B | |
| SCHEMBL19426444 | 0.92 | CYP19A1 (0.50) | ARHPGDCYP19A1ALDH1A1PDE4B | |
| SCHEMBL19575062 | 0.88 | CYP19A1 (0.47) | ARHPGDCYP19A1ALDH1A1PDE4B | |
| SCHEMBL19280740 | 0.87 | CYP19A1 (0.54) | ARESR1ESR2HPGDCYP19A1 | |
| SCHEMBL30473827 | 0.87 | CYP19A1 (0.54) | ARESR1ESR2HPGDCYP19A1 | |
| SCHEMBL12149421 | 0.87 | CYP19A1 (0.52) | ARHPGDCYP19A1ALDH1A1PDE4B | |
| SCHEMBL15353786 | 0.87 | AR (0.50) | ARHPGDCYP3A4CYP19A1ALDH1A1 | |
| SCHEMBL1501411 | 0.87 | ALDH1A1 (0.53) | ARHPGDCYP19A1ALDH1A1PDE4B | |
| SCHEMBL19426415 | 0.85 | CYP19A1 (0.48) | ARESR1ESR2HPGDCYP19A1 | |
| SCHEMBL12256413 | 0.85 | CYP19A1 (0.42) | ARHPGDCYP19A1ALDH1A1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9394404-B2 | Synthesis and polymerization of oligomeric aliphatic-aromatic based phthalonitriles | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2016-07-19 | — | — | US | disclosed |
| US-20160168326-A1 | SYNTHESIS AND POLYMERIZATION OF OLIGOMERIC ALIPHATIC-AROMATIC BASED PHTHALONITRILES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168326-A1 | SYNTHESIS AND POLYMERIZATION OF OLIGOMERIC ALIPHATIC-AROMATIC BASED PHTHALONITRILES | AHR, NR4A1, ARNT | AR 5/4885ESR1 1007/4885ESR2 478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.