Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7885818 | 0.90 | MAPT (0.44) | MAPTALDH1A1CYP3A4CYP2C9PKM | |
| SCHEMBL23068158 | 0.77 | MEN1 (0.46) | MAPTALDH1A1CYP3A4CYP2C9PKM | |
| SCHEMBL31715683 | 0.75 | MEN1 (0.41) | MAPTALDH1A1CYP3A4CYP2C9PKM | |
| SCHEMBL31715768 | 0.73 | MEN1 (0.40) | MAPTALDH1A1CYP3A4CYP2C9PKM | |
| SCHEMBL2161839 | 0.73 | MAPT (0.49) | MAPTALDH1A1CYP3A4CYP2C9PKM | |
| SCHEMBL9082004 | 0.73 | ALDH1A1 (0.49) | MAPTALDH1A1CYP3A4CYP2C9PKM | |
| SCHEMBL9084023 | 0.71 | MAPT (0.47) | MAPTALDH1A1CYP3A4CYP2C9PKM | |
| SCHEMBL11256559 | 0.71 | MAPT (0.47) | MAPTALDH1A1CYP3A4CYP2C9PKM | |
| SCHEMBL9083880 | 0.71 | MAPT (0.47) | MAPTALDH1A1CYP3A4CYP2C9PKM | |
| Hydrochloric Acid SCHEMBL7548680 | 0.70 | MAPT (0.46) | MAPTALDH1A1CYP3A4CYP2C9PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3034063-B1 | DENTAL MATERIAL INCLUDING 1-CYCLOHEXYL-5-PROPYL-BARBITURIC ACID POLYMERIZATION CATALYST | SHOFU INC (JP) | 2022-01-19 | — | — | EP | disclosed |
| CN-105713115-B | Dental material containing propyl barbituric acid polymerization catalyst | 株式会社松风 | 2021-04-16 | — | — | CN | disclosed |
| US-10363202-B2 | Dental material including propylbarbituric acid polymerization catalyst | SHOFU INC. (JP) | 2019-07-30 | — | — | US | disclosed |
| US-20160175203-A1 | DENTAL MATERIAL INCLUDING PROPYLBARBITURIC ACID POLYMERIZATION CATALYST | SHOFU INC. (JP) | 2016-06-23 | — | — | US | disclosed |
| EP-3034063-A1 | DENTAL MATERIAL INCLUDING 1-CYCLOHEXYL-5-PROPYLBARBITURIC ACID POLYMERIZATION CATALYST | Shofu Inc. (JP) | 2016-06-22 | — | — | EP | disclosed |