Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31715683 | 0.98 | MEN1 (0.41) | MEN1KMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL7885818 | 0.76 | MAPT (0.44) | MEN1KMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL17835296 | 0.73 | MAPT (0.42) | MEN1KMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL11600178 | 0.73 | HBB (0.50) | MEN1KMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL7864240 | 0.71 | MAPT (0.47) | MEN1KMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL145904 | 0.69 | MAPT (0.49) | MEN1KMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL14185382 | 0.69 | MEN1 (0.46) | MEN1KMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL7338888 | 0.68 | TSHR (0.46) | MEN1KMT2AMAPTTDP1CYP1B1 | |
| SCHEMBL27390779 | 0.67 | TSHR (0.44) | MEN1KMT2AMAPTTDP1CYP1B1 | |
| SCHEMBL23068158 | 0.66 | MEN1 (0.46) | MEN1KMT2AMAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025226892-A1 | SPIROCYCLE-CONTAINING DIAMINOMETHYLENE PYRIMIDINE-2,4,6-TRIONE AGONISTS OF PARATHYROID HORMONE 1 AND INCRETIN RECEPTORS | SEPTERNA, INC. (US) | 2025-10-30 | — | — | WO | disclosed |