SCHEMBL17835393

SCHEMBL17835393

CO[Si](Br)(OC)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 2/20 0.38
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
POLB P06746 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
ALDH1A1 P00352 3/20 0.32
LTA4H P09960 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.32
BBOX1 O75936 1/20 0.32
EHMT2 Q96KQ7 1/20 0.32
EHMT1 Q9H9B1 1/20 0.32
MAPT P10636 2/20 0.31
TSHR P16473 3/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18108399 0.84 CA4 (0.41) CA4LTA4HTSHR
SCHEMBL18108309 0.83 TSHR (0.32) CA4LTA4HMAPTTSHR
SCHEMBL18108065 0.79 CA4 (0.38) CA4ESR1ESR2POLBCA12
SCHEMBL18108221 0.79 CA4 (0.38) CA4ESR1ESR2POLBCA12
SCHEMBL18108503 0.77 ESR1 (0.38) CA4ESR1ESR2POLBCA12
SCHEMBL17835346 0.77 ACHE (0.40) CA1CA2CA7CA9ALDH1A1
SCHEMBL18108034 0.75 CA4 (0.35) CA4ESR1ESR2POLBCA12
SCHEMBL18108133 0.75 CA4 (0.35) CA4ESR1ESR2POLBCA12
SCHEMBL646249 0.75 CA4 (0.43) CA4ESR1ESR2POLBCA12
SCHEMBL6762255 0.73 ESR1 (0.35) CA4ESR1ESR2POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3034543-B1 CURABLE COMPOSITION, CURING PRODUCT, AND METHOD FOR USING CURABLE COMPOSITION LINTEC CORP (JP) 2021-03-31 EP disclosed
US-9884928-B2 Polymers functionalized with activated nitrogen heterocycles containing a pendant functional group BRIDGESTONE CORPORATION (JP) 2018-02-06 US disclosed
US-9670326-B2 Curable composition, curing product, and method for using curable composition LINTEC CORPORATION (JP) 2017-06-06 US disclosed
US-9540490-B2 Curable composition, curing product, and method for using curable composition LINTEC CORPORATION (JP) 2017-01-10 US disclosed
US-20160289354-A1 POLYMERS FUNCTIONALIZED WITH ACTIVATED NITROGEN HETEROCYCLES CONTAINING A PENDANT FUNCTIONAL GROUP BRIDGESTONE CORPORATION (JP) 2016-10-06 US disclosed
US-20160229961-A1 CURABLE COMPOSITION, CURING PRODUCT, AND METHOD FOR USING CURABLE COMPOSITION LINTEC CORPORATION (JP) 2016-08-11 US disclosed
US-20160208054-A1 CURABLE COMPOSITION, CURING PRODUCT, AND METHOD FOR USING CURABLE COMPOSITION LINTEC CORPORATION (JP) 2016-07-21 US disclosed
EP-3034543-A1 CURABLE COMPOSITION, CURING PRODUCT, AND METHOD FOR USING CURABLE COMPOSITION Lintec Corporation (JP) 2016-06-22 EP disclosed