SCHEMBL17835969

SCHEMBL17835969

Br[Ni]Br.Cc1cccc(C)c1N=C1C(=Nc2c(C)cccc2C)c2cccc3cccc1c23

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.44
MEN1 O00255 5/20 0.39
KMT2A Q03164 5/20 0.39
ALDH1A1 P00352 9/20 0.39
HSD17B10 Q99714 5/20 0.39
TSHR P16473 3/20 0.39
MAPK1 P28482 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
ATM Q13315 2/20 0.39
CES2 O00748 1/20 0.36
BCHE P06276 1/20 0.36
CES1 P23141 1/20 0.36
MCL1 Q07820 1/20 0.36
HPGD P15428 4/20 0.35
CASP1 P29466 2/20 0.35
CASP7 P55210 2/20 0.35
TP53 P04637 1/20 0.35
HIF1A Q16665 1/20 0.35
TYMS P04818 2/20 0.35
ACHE P22303 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5588472 0.93 POLB (0.49) POLBMEN1KMT2AALDH1A1HSD17B10
SCHEMBL5588478 0.93 POLB (0.49) POLBMEN1KMT2AALDH1A1HSD17B10
SCHEMBL21563329 0.93 POLB (0.49) POLBMEN1KMT2AALDH1A1HSD17B10
SCHEMBL5588451 0.91 POLB (0.47) POLBMEN1KMT2AALDH1A1HSD17B10
Bromide SCHEMBL17835968 0.89 POLB (0.46) POLBMEN1KMT2AALDH1A1HSD17B10
SCHEMBL15624720 0.83 POLB (0.42) POLBMEN1KMT2AALDH1A1HSD17B10
SCHEMBL21563330 0.83 POLB (0.45) POLBMEN1KMT2AALDH1A1HSD17B10
SCHEMBL2231358 0.81 ALDH1A1 (0.53) POLBMEN1KMT2AALDH1A1HSD17B10
SCHEMBL2231354 0.81 ALDH1A1 (0.53) POLBMEN1KMT2AALDH1A1HSD17B10
SCHEMBL5589772 0.80 POLB (0.40) POLBMEN1KMT2AALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3237461-B1 PROCESS FOR THE PREPARATION OF A POLYOLEFIN HAVING ONE OR MULTIPLE END-FUNCTIONALIZED BRANCHES SABIC GLOBAL TECHNOLOGIES BV (NL) 2026-03-18 EP disclosed
CN-120136933-A Large steric hindrance substituent modified acenaphthylene skeleton Ni complex and synthesis method and application thereof 中国科学院化学研究所 2025-06-13 CN disclosed
EP-3034545-B1 A PROCESS FOR THE PREPARATION OF A GRAFT COPOLYMER COMPRISING A POLYOLEFIN MAIN CHAIN AND ONE OR A MULTIPLE POLYMER SIDE CHAINS AND THE PRODUCTS OBTAINED THEREFROM SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-11-04 EP disclosed
US-10787545-B2 Process for the preparation of polyolefin-based graft copolymers comprising a first functionalized short chain branched polyolefin block and one or multiple polymer side chains SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-09-29 US disclosed
US-20200262983-A1 PROCESS FOR THE PREPARATION OF POLYOLEFIN-BASED GRAFT COPOLYMERS COMPRISING A FIRST FUNCTIONALIZED SHORT CHAIN BRANCHED POLYOLEFIN BLOCK AND ONE OR MULTIPLE POLYMER SIDE CHAINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-08-20 US disclosed
US-10717826-B2 Process for the preparation of polyolefin-based graft copolymers comprising a first long chain branched polyolefin block and one or multiple polymer side chains SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-07-21 US disclosed
EP-3233974-B1 A PROCESS FOR THE PREPARATION OF A BLOCK COPOLYMER COMPRISING A FIRST POLYOLEFIN BLOCK AND A SECOND POLYMER BLOCK SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-02-19 EP disclosed
US-10472447-B2 Process for the preparation of a graft copolymer comprising a polyolefin main chain and one or a multiple polymer side chains and the products obtained therefrom SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-11-12 US disclosed
US-10465018-B2 Process for the preparation of a polyolefin having one or multiple end-functionalized branches SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-11-05 US disclosed
US-10450388-B2 Process for the preparation of a branched polyolefin SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-10-22 US disclosed
EP-3037438-A1 Process for the preparation of a branched polyolefin SABIC Global Technologies B.V. (NL) 2016-06-29 EP disclosed
EP-3037437-A1 Process for the preparation of a polyolefin having one or multiple end-functionalized branches. SABIC Global Technologies B.V. (NL) 2016-06-29 EP disclosed
WO-2016097204-A1 A PROCESS FOR THE PREPARATION OF A GRAFT COPOLYMER COMPRISING A POLYOLEFIN MAIN CHAIN AND ONE OR A MULTIPLE POLYMER SIDE CHAINS AND THE PRODUCTS OBTAINED THEREFROM SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-06-23 WO disclosed
WO-2016097208-A1 A PROCESS FOR THE PREPARATION OF A BLOCK COPOLYMER COMPRISING A FIRST POLYOLEFIN BLOCK AND A SECOND POLYMER BLOCK AND THE PRODUCTS OBTAINED THEREFROM SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-06-23 WO disclosed
WO-2016097207-A1 A PROCESS FOR THE PREPARATION OF A GRAFT COPOLYMER COMPRISING A POLYOLEFIN MAIN CHAIN AND ONE OR A MULTIPLE POLYMER SIDE CHAINS AND THE PRODUCTS OBTAINED THEREFROM SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-06-23 WO disclosed
WO-2016097203-A1 A PROCESS FOR THE PREPARATION OF A BLOCK COPOLYMER COMPRISING A FIRST POLYOLEFIN BLOCK AND A SECOND POLYMER BLOCK AS WELL AS THE PRODUCTS OBTAINED THEREFROM SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-06-23 WO disclosed
EP-3034547-A1 A process for the preparation of a block copolymer comprising a first polyolefin block and a second polymer block and the products obtained therefrom SABIC Global Technologies B.V. (NL) 2016-06-22 EP disclosed
EP-3034544-A1 A process for the preparation of a graft copolymer comprising a polyolefin main chain and one or a multiple polymer side chains and the products obtained therefrom SABIC Global Technologies B.V. (NL) 2016-06-22 EP disclosed
EP-3034545-A1 A process for the preparation of a graft copolymer comprising a polyolefin main chain and one or a multiple polymer side chains and the products obtained therefrom SABIC Global Technologies B.V. (NL) 2016-06-22 EP disclosed
EP-3034546-A1 A process for the preparation of a block copolymer comprising a first polyolefin block and a second polymer block as well as the products obtained therefrom SABIC Global Technologies B.V. (NL) 2016-06-22 EP disclosed