Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5588472 | 0.89 | POLB (0.49) | POLBALDH1A1MAPK1HSD17B10TSHR | |
| SCHEMBL5588478 | 0.89 | POLB (0.49) | POLBALDH1A1MAPK1HSD17B10TSHR | |
| SCHEMBL21563329 | 0.89 | POLB (0.49) | POLBALDH1A1MAPK1HSD17B10TSHR | |
| SCHEMBL5588451 | 0.88 | POLB (0.47) | POLBALDH1A1MAPK1HSD17B10TSHR | |
| Bromide SCHEMBL17835968 | 0.86 | POLB (0.46) | POLBALDH1A1MAPK1HSD17B10TSHR | |
| SCHEMBL17835969 | 0.83 | POLB (0.44) | POLBALDH1A1MAPK1HSD17B10TSHR | |
| SCHEMBL15624720 | 0.80 | POLB (0.42) | POLBALDH1A1MAPK1HSD17B10TSHR | |
| SCHEMBL2231358 | 0.78 | ALDH1A1 (0.53) | POLBALDH1A1MAPK1HSD17B10TSHR | |
| SCHEMBL2231354 | 0.78 | ALDH1A1 (0.53) | POLBALDH1A1MAPK1HSD17B10TSHR | |
| SCHEMBL31619763 | 0.78 | ALDH1A1 (0.44) | POLBALDH1A1MAPK1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019217930-A1 | LIGHT AS CATALYTIC SWITCH: METAL-ORGANIC INSERTION/LIGHT INITIATED RADICAL (MILRad) POLYMERIZATION | UNIVERSITY OF HOUSTON SYSTEM (US) | 2019-11-14 | — | — | WO | disclosed |