Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | SHBG | P04278 | 2/20 | 0.40 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.40 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.40 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.40 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.40 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.40 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.40 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.40 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL103636 | 1.00 | ESR1 (0.41) | ESR1ESR2CYP19A1LMNAGPBAR1 | |
| SCHEMBL16303298 | 1.00 | ESR1 (0.41) | ESR1ESR2CYP19A1LMNAGPBAR1 | |
| SCHEMBL103223 | 1.00 | ESR1 (0.41) | ESR1ESR2CYP19A1LMNAGPBAR1 | |
| SCHEMBL13261217 | 1.00 | ESR1 (0.41) | ESR1ESR2CYP19A1LMNAGPBAR1 | |
| SCHEMBL137499 | 1.00 | ESR1 (0.41) | ESR1ESR2CYP19A1LMNAGPBAR1 | |
| SCHEMBL15307855 | 0.83 | — | — | |
| SCHEMBL15307857 | 0.83 | — | — | |
| SCHEMBL24623303 | 0.80 | GPBAR1 (0.68) | ESR1ESR2CYP19A1LMNAGPBAR1 | |
| SCHEMBL2847894 | 0.80 | GPBAR1 (0.68) | ESR1ESR2CYP19A1LMNAGPBAR1 | |
| SCHEMBL2593987 | 0.80 | GPBAR1 (0.68) | ESR1ESR2CYP19A1LMNAGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058977-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING TUBERCULOSIS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058977-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING TUBERCULOSIS | FNTB, DCXR, TREH | ESR1 4665/4885ESR2 4401/4885CYP19A1 4297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.