SCHEMBL1783796

SCHEMBL1783796

CN1C(=O)c2ccc(Br)cc2C1=O

nearest known ligand 0.66

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
APP P05067 6/20 0.66
ALDH1A1 P00352 4/20 0.55
ESR1 P03372 1/20 0.55
ESR2 Q92731 1/20 0.55
S100A4 P26447 1/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
MAPT P10636 2/20 0.52
HSD17B10 Q99714 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
ALOX15 P16050 1/20 0.52
POLB P06746 2/20 0.50
RXFP1 Q9HBX9 1/20 0.50
HPGD P15428 1/20 0.50
MAPK1 P28482 1/20 0.50
NPC1 O15118 1/20 0.50
DDB1 Q16531 1/20 0.47
CRBN Q96SW2 1/20 0.47
CASP3 P42574 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25914505 0.84 APP (0.50) APPALDH1A1ESR1ESR2S100A4
SCHEMBL9810842 0.79 ALDH1A1 (0.58) APPALDH1A1ESR1ESR2S100A4
SCHEMBL3024023 0.78 APP (0.66) APPALDH1A1ESR1ESR2MEN1
SCHEMBL6651899 0.78 ESR1 (0.59) APPALDH1A1ESR1ESR2S100A4
SCHEMBL19200191 0.78 ESR1 (0.50) APPALDH1A1ESR1ESR2S100A4
SCHEMBL585483 0.78 POLB (0.57) APPALDH1A1ESR1ESR2S100A4
SCHEMBL1686814 0.78 ESR1 (0.50) APPALDH1A1ESR1ESR2S100A4
SCHEMBL10053401 0.77 ALDH1A1 (0.59) APPALDH1A1MEN1KMT2AMAPT
SCHEMBL7519644 0.76 ALDH1A1 (0.63) ALDH1A1ESR1ESR2MEN1KMT2A
SCHEMBL2616778 0.76 APP (0.67) APPALDH1A1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504556-A Bisphenol phthaloyl Process for producing imine 潍坊弘润石化科技有限公司 2025-02-25 CN claimed
CN-117567411-A Polyimide dianhydride monomer capable of realizing bidirectional polymerization and synthesis method thereof 仪征市海帆化工有限公司 2024-02-20 CN claimed
CN-117247367-A Novel polyimide dianhydride monomer and synthesis method thereof 邹从伟 2023-12-19 CN claimed
CN-108727277-B Singlet oxygen highly selective aggregation-induced chemiluminescence probe and preparation method and application thereof 陕西师范大学 2021-03-30 CN claimed
CN-103965094-B The synthetic method of the N-methyl-4-bromo-phthalimide of amino-5- 江苏道博化工有限公司 2016-07-06 CN claimed
EP-0411304-B1 Acetylene bis-phthalic compounds and polyimides made therefrom GEN ELECTRIC (US) 1994-06-15 EP claimed
EP-0411304-A1 Acetylene bis-phthalic compounds and polyimides made therefrom GENERAL ELECTRIC COMPANY (US) 1991-02-06 EP claimed
US-20260125378-A2 Heterocyclic Compounds BEONE MEDICINES I GMBH (CH) 2026-05-07 US disclosed
EP-4720065-A1 PRMT5 INHIBITORS AND USES THEREOF Insilico Medicine IP Limited (HK) 2026-04-08 EP disclosed
EP-4658650-A1 HETEROCYCLIC COMPOUNDS Beone Medicines I GmbH (CH) 2025-12-10 EP disclosed
US-20250353846-A1 Heterocyclic Compounds BEONE MEDICINES I GMBH (CH) 2025-11-20 US disclosed
WO-2025067457-A1 HETEROCYCLIC FUSED RING COMPOUND, AND COMPOSITION AND USE THEREOF 深圳市塔吉瑞生物医药有限公司 2025-04-03 WO disclosed
CN-119504556-A Bisphenol phthaloyl Process for producing imine 潍坊弘润石化科技有限公司 2025-02-25 CN disclosed
EP-1709022-A1 SELECTIVE ESTROGEN RECEPTOR MODULATORS ELI LILLY AND COMPANY (US) 2006-10-11 EP disclosed
WO-2005073205-A1 SELECTIVE ESTROGEN RECEPTOR MODULATORS ELI LILLY AND COMPANY (US) 2005-08-11 WO disclosed
US-6191307-B1 Process for making benzoic acids ALBEMARLE CORPORATION 2001-02-20 US disclosed
EP-0763521-A2 Method of recycling phase transfer catalyst for displacement reactions GENERAL ELECTRIC COMPANY (US) 1997-03-19 EP disclosed
EP-0411304-B1 Acetylene bis-phthalic compounds and polyimides made therefrom GEN ELECTRIC (US) 1994-06-15 EP disclosed
EP-0411304-A1 Acetylene bis-phthalic compounds and polyimides made therefrom GENERAL ELECTRIC COMPANY (US) 1991-02-06 EP disclosed
US-4973707-A Acetylene bis-phthalic compounds and polyimides made therefrom GENERAL ELECTRIC COMPANY (US) 1990-11-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125378-A2 Heterocyclic Compounds NFATC1, CD4, MALT1 APP 3736/4885ALDH1A1 2837/4885ESR1 1922/4885
US-20250353846-A1 Heterocyclic Compounds NFATC1, CD4, ACIN1 APP 3889/4885ALDH1A1 1006/4885ESR1 1935/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.