SCHEMBL1783797

SCHEMBL1783797

O=C(Cl)c1ccc2oc3ccccc3c(=O)c2c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 8/20 0.74
NPC1 O15118 3/20 0.72
RAB9A P51151 2/20 0.72
MAOA P21397 4/20 0.61
KDM4E B2RXH2 1/20 0.58
ALDH1A1 P00352 1/20 0.58
GLA P06280 1/20 0.58
CYP3A4 P08684 1/20 0.58
MAPT P10636 1/20 0.58
HPGD P15428 1/20 0.58
PGAM1 P18669 1/20 0.58
CASP1 P29466 1/20 0.58
CASP7 P55210 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
HSD17B10 Q99714 1/20 0.58
POLB P06746 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
TBK1 Q9UHD2 1/20 0.51
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11749377 0.92 TTR (0.63) TTRNPC1RAB9AMAOAKDM4E
SCHEMBL3964072 0.90 TTR (0.74) TTRNPC1RAB9AMAOAKDM4E
SCHEMBL28414324 0.89 TTR (0.64) TTRNPC1RAB9AMAOAKDM4E
SCHEMBL9535481 0.88 TTR (0.57) TTRNPC1RAB9AMAOAKDM4E
SCHEMBL1787556 0.85 TTR (1.00) TTRNPC1RAB9AMAOAKDM4E
SCHEMBL27753628 0.85 TTR (0.77) TTRNPC1RAB9AMAOAKDM4E
Hydrochloric Acid SCHEMBL11367851 0.84 TTR (0.97) TTRNPC1RAB9AMAOAKDM4E
SCHEMBL27753626 0.84 TTR (0.74) TTRNPC1RAB9AMAOAKDM4E
SCHEMBL10882826 0.84 NPC1 (1.00) TTRNPC1RAB9AMAOAKDM4E
SCHEMBL6242650 0.83 TTR (0.77) TTRNPC1RAB9AMAOAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102675673-B Ultraviolet ray assisted surface modification method and product with surface formed thereby BEIJING WANHE XINYUAN BIOLOG TECHNOLOGY CO LTD 2014-08-13 CN disclosed
CN-102675672-B Ultraviolet aided surface modification method and product with surface formed by method BEIJING WANHE XINYUAN BIOLOG TECHNOLOGY CO LTD 2014-06-18 CN disclosed
CN-102702556-B Ultraviolet-assisted surface modification method and product with surface formed thereby BEIJING WANHE XINYUAN BIOLOG TECHNOLOGY CO LTD 2014-03-05 CN disclosed
CN-102643447-B Ultraviolet light assisted surface modification method and product with surface formed by means of method BEIJING WANHEXINYUAN BIOTECHNOLOGIES CO LTD 2013-07-24 CN disclosed
US-8323750-B2 Method of ultraviolet light assisted surface modification and product having a surface formed by this method BEIJING WANHEXINYUAN BIOTECHNOLOGY CO., LTD. (CN) 2012-12-04 US disclosed
US-8323750-B2 Method of ultraviolet light assisted surface modification and product having a surface formed by this method BEIJING WANHEXINYUAN BIOTECHNOLOGY CO., LTD. (CN) 2012-12-04 US disclosed
US-8323750-B2 Method of ultraviolet light assisted surface modification and product having a surface formed by this method BEIJING WANHEXINYUAN BIOTECHNOLOGY CO., LTD. (CN) 2012-12-04 US disclosed
CN-102702556-A Ultraviolet-assisted surface modification method and product with surface formed thereby BEIJING WANHE XINYUAN BIOLOG TECHNOLOGY CO LTD 2012-10-03 CN disclosed
CN-102675673-A Ultraviolet ray assisted surface modification method and product with surface formed thereby BEIJING WANHE XINYUAN BIOLOG TECHNOLOGY CO LTD 2012-09-19 CN disclosed
CN-102675672-A Ultraviolet aided surface modification method and product with surface formed by method BEIJING WANHE XINYUAN BIOLOG TECHNOLOGY CO LTD 2012-09-19 CN disclosed
CN-101372538-B Ultraviolet light assisted surface modification method and product with surface formed by method BEIJING WANHE XINYUAN BIOTECHNOLOGY CO LTD 2012-08-29 CN disclosed
CN-102643447-A Ultraviolet light assisted surface modification method and product with surface formed by means of method BEIJING WANHEXINYUAN BIOTECHNOLOGIES CO LTD 2012-08-22 CN disclosed
US-20110124766-A1 METHOD OF ULTRAVIOLET LIGHT ASSISTED SURFACE MODIFICATION AN PRODUCT HAVING A SURFACE FORMED BY THIS METHOD BEIJING WANHEXINYUAN BIOTECHNOLOGY CO., LTD. (CN) 2011-05-26 US disclosed
US-20110124766-A1 METHOD OF ULTRAVIOLET LIGHT ASSISTED SURFACE MODIFICATION AN PRODUCT HAVING A SURFACE FORMED BY THIS METHOD BEIJING WANHEXINYUAN BIOTECHNOLOGY CO., LTD. (CN) 2011-05-26 US disclosed
US-20110124766-A1 METHOD OF ULTRAVIOLET LIGHT ASSISTED SURFACE MODIFICATION AN PRODUCT HAVING A SURFACE FORMED BY THIS METHOD BEIJING WANHEXINYUAN BIOTECHNOLOGY CO., LTD. (CN) 2011-05-26 US disclosed
CN-101372538-A Ultraviolet light assisted surface modification method and product with surface formed by method BEIJING WANHE XINYUAN BIOTECHN (CN) 2009-02-25 CN disclosed
US-4250097-A (7-METHYL(2-HYDROXYETHYL)AMINO)SULFONYLXANTHONE-2-CARBOXYLIC ACID; ENZYME INHIBITORS SYNTEX (U.S.A.) INC. (US) 1981-02-10 US disclosed
US-4232040-A XANTHONE CARBOXYLIC ACIDS SYNTEX (U.S.A.) INC. (US) 1980-11-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110124766-A1 METHOD OF ULTRAVIOLET LIGHT ASSISTED SURFACE MODIFICATION AN PRODUCT HAVING A SURFACE FORMED BY THIS METHOD XPA, CYBA, PROC TTR 3486/4885NPC1 3805/4885RAB9A 3050/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.