Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | BCAT1 | P54687 | 6/20 | 0.52 |
| ▸ | AHR | P35869 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11747762 | 0.91 | TTR (0.50) | TTRNPC1RAB9ABCAT1AHR | |
| SCHEMBL10788381 | 0.89 | TTR (0.61) | TTRNPC1RAB9AAHRKDM4E | |
| SCHEMBL1783797 | 0.88 | TTR (0.74) | TTRNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL9691287 | 0.87 | TTR (0.51) | TTRNPC1RAB9ABCAT1KDM4E | |
| SCHEMBL1222307 | 0.84 | TTR (0.78) | TTRNPC1RAB9ABCAT1KDM4E | |
| SCHEMBL11352725 | 0.83 | TTR (0.54) | TTRNPC1RAB9ABCAT1AHR | |
| SCHEMBL1283826 | 0.82 | NPC1 (0.79) | TTRNPC1RAB9ABCAT1KDM4E | |
| SCHEMBL6307220 | 0.82 | CHEK2 (0.59) | TTRNPC1RAB9ABCAT1AHR | |
| SCHEMBL29886877 | 0.82 | CHEK2 (0.59) | TTRNPC1RAB9ABCAT1AHR | |
| SCHEMBL30765635 | 0.82 | NPC1 (0.79) | TTRNPC1RAB9ABCAT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3953400-A | Polyketones and methods therefor | RAYCHEM CORPORATION (US) | 1976-04-27 | — | — | US | claimed |
| EP-0178183-B1 | PREPARATION OF AROMATIC KETONE-SULFONE COPOLYMERS | RAYCHEM CORPORATION (a Delaware corporation) (US) | 1993-01-20 | — | — | EP | disclosed |
| US-4593086-A | From carboxylic acid halide and aromatic dicarboxylic acid dihalide | RAYCHEM CORPORATION (US) | 1986-06-03 | — | — | US | disclosed |
| EP-0178183-A2 | Preparation of aromatic ketone-sulfone copolymers | RAYCHEM CORPORATION (a Delaware corporation) (US) | 1986-04-16 | — | — | EP | disclosed |
| EP-0069597-B1 | PREPARING P-PHENOXY-BENZOYL COMPOUNDS | RAYCHEM CORPORATION (a California corporation) (US) | 1984-10-10 | — | — | EP | disclosed |
| US-4474990-A | Preparing p-phenoxy benzoyl compounds | RAYCHEM CORPORATION (US) | 1984-10-02 | — | — | US | disclosed |
| EP-0069597-A1 | Preparing p-phenoxy-benzoyl compounds | RAYCHEM CORPORATION (a California corporation) (US) | 1983-01-12 | — | — | EP | disclosed |
| US-4229564-A | SUITABLE FOR MELT PROCESSING AND EXTRUSION COATINGS | RAYCHEM CORPORATION (US) | 1980-10-21 | — | — | US | disclosed |
| US-4024314-A | Electrical conductor insulated by a polyketones | RAYCHEM CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |
| US-3953400-A | Polyketones and methods therefor | RAYCHEM CORPORATION (US) | 1976-04-27 | — | — | US | disclosed |