SCHEMBL1787556

SCHEMBL1787556

O=C(O)c1ccc2oc3ccccc3c(=O)c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 10/20 1.00
NPC1 O15118 2/20 0.74
RAB9A P51151 2/20 0.74
MAOA P21397 2/20 0.63
KDM4E B2RXH2 2/20 0.60
ALDH1A1 P00352 2/20 0.60
HPGD P15428 2/20 0.60
HSD17B10 Q99714 2/20 0.60
MEN1 O00255 1/20 0.60
TP53 P04637 1/20 0.60
CYP2C9 P11712 1/20 0.60
PTGER1 P34995 1/20 0.60
PTGER3 P43115 1/20 0.60
PTGER2 P43116 1/20 0.60
KMT2A Q03164 1/20 0.60
PTGDR Q13258 1/20 0.60
GLA P06280 1/20 0.60
CYP3A4 P08684 1/20 0.60
MAPT P10636 1/20 0.60
PGAM1 P18669 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11367851 0.98 TTR (0.97) TTRNPC1RAB9AMAOAKDM4E
SCHEMBL68189 0.91 TTR (0.83) TTRNPC1RAB9AMAOAKDM4E
SCHEMBL490420 0.90 TTR (1.00) TTRNPC1RAB9AMAOAKDM4E
Hydrochloric Acid SCHEMBL11749391 0.90 TTR (0.81) TTRNPC1RAB9AMAOAKDM4E
SCHEMBL11322640 0.88 TTR (0.80) TTRNPC1RAB9AMAOAKDM4E
SCHEMBL1222307 0.88 TTR (0.78) TTRNPC1RAB9AKDM4EALDH1A1
SCHEMBL6242650 0.87 TTR (0.77) TTRNPC1RAB9AMAOAKDM4E
SCHEMBL27753628 0.87 TTR (0.77) TTRNPC1RAB9AMAOAKDM4E
Xanthone SCHEMBL28077164 0.86 TTR (0.75) TTRNPC1RAB9AMAOAKDM4E
SCHEMBL1783797 0.85 TTR (0.74) TTRNPC1RAB9AMAOAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116903580-A Single-component thioxanthone photoinitiator applicable to UV-LED curing system and preparation and application thereof 大连理工大学 2023-10-20 CN disclosed
US-8735167-B2 Photoinduced signal amplification through externally sensitized photofragmentation in masked photosensitizers and photoamplified fluorescence turn-off system COLORADO SEMINARY, WHICH OWNS AND OPERATES THE UNIVERSITY OF DENVER (US) 2014-05-27 US disclosed
US-8735167-B2 Photoinduced signal amplification through externally sensitized photofragmentation in masked photosensitizers and photoamplified fluorescence turn-off system COLORADO SEMINARY, WHICH OWNS AND OPERATES THE UNIVERSITY OF DENVER (US) 2014-05-27 US disclosed
US-8323750-B2 Method of ultraviolet light assisted surface modification and product having a surface formed by this method BEIJING WANHEXINYUAN BIOTECHNOLOGY CO., LTD. (CN) 2012-12-04 US disclosed
US-20110124766-A1 METHOD OF ULTRAVIOLET LIGHT ASSISTED SURFACE MODIFICATION AN PRODUCT HAVING A SURFACE FORMED BY THIS METHOD BEIJING WANHEXINYUAN BIOTECHNOLOGY CO., LTD. (CN) 2011-05-26 US disclosed
US-20110117667-A1 PHOTOINDUCED SIGNAL AMPLIFICATION THROUGH EXTERNALLY SENSITIZED PHOTOFRAGMENTATION IN MASKED PHOTOSENSITIZERS AND PHOTOAMPLIFIED FLUORESCENCE TURN-OFF SYSTEM COLORADO SEMINARY, WHICH OWNS AND OPERATES THE UNIVERSITY OF DENVER 2011-05-19 US disclosed
US-20110117667-A1 PHOTOINDUCED SIGNAL AMPLIFICATION THROUGH EXTERNALLY SENSITIZED PHOTOFRAGMENTATION IN MASKED PHOTOSENSITIZERS AND PHOTOAMPLIFIED FLUORESCENCE TURN-OFF SYSTEM COLORADO SEMINARY, WHICH OWNS AND OPERATES THE UNIVERSITY OF DENVER 2011-05-19 US disclosed
US-20090247420-A1 METHOD FOR ENCODING AND SCREENING COMBINATORIAL LIBRARIES NATIONAL SCIENCE FOUNDATION 2009-10-01 US disclosed
US-20090247420-A1 METHOD FOR ENCODING AND SCREENING COMBINATORIAL LIBRARIES NATIONAL SCIENCE FOUNDATION 2009-10-01 US disclosed
US-20090247420-A1 METHOD FOR ENCODING AND SCREENING COMBINATORIAL LIBRARIES NATIONAL SCIENCE FOUNDATION 2009-10-01 US disclosed
US-4024276-A ANTIALLERGIC ROUSSEL-UCLAF (FR) 1977-05-17 US disclosed
US-3989721-A Disubstituted xanthone carboxylic acid compounds SYNTEX (U.S.A.) INC. (US) 1976-11-02 US disclosed
US-3989720-A Disubstituted xanthone carboxylic acid compounds SYNTEX (U.S.A.) INC. (US) 1976-11-02 US disclosed
US-3988352-A Disubstituted xanthone carboxylic acid compounds SYNTEX (U.S.A.) INC. (US) 1976-10-26 US disclosed
US-3979414-A Disubstituted xanthone carboxylic acid compounds SYNTEX (U.S.A.) INC. (US) 1976-09-07 US disclosed
US-3965115-A Disubstituted xanthone carboxylic acid compounds SYNTEX (U.S.A.) INC. (US) 1976-06-22 US disclosed
US-3963753-A Disubstituted xanthone carboxylic acid compounds SYNTEX (U.S.A.) INC. (US) 1976-06-15 US disclosed
US-3963752-A Disubstituted xanthone carboxylic acid compounds SYNTEX (U.S.A.) INC. (US) 1976-06-15 US disclosed
US-3951618-A Method of use of, and compositions containing, disubstituted xanthone carboxylic acid compounds SYNTEX (U.S.A.) INC. (US) 1976-04-20 US disclosed
US-3949084-A Novel substituted xanthone carboxylic acid compounds SYNTEX (U.S.A.) INC. (US) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110124766-A1 METHOD OF ULTRAVIOLET LIGHT ASSISTED SURFACE MODIFICATION AN PRODUCT HAVING A SURFACE FORMED BY THIS METHOD XPA, CYBA, PROC TTR 3486/4885NPC1 3805/4885RAB9A 3050/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.