Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2139326 | 1.00 | USP2 (0.47) | USP2THRBCYP3A4SMN1; SMN2LMNA | |
| SCHEMBL7545745 | 0.98 | USP2 (0.44) | USP2THRBCYP3A4SMN1; SMN2LMNA | |
| SCHEMBL7116256 | 0.91 | USP2 (0.45) | USP2THRBCYP3A4SMN1; SMN2LMNA | |
| 1,6-Hexanediol SCHEMBL28881383 | 0.91 | USP2 (0.54) | USP2THRBLMNAKDM4EDUSP3 | |
| SCHEMBL129740 | 0.91 | KDM4E (0.34) | USP2THRBCYP3A4KDM4EPTPN1 | |
| 1,4-Butanediol SCHEMBL11042082 | 0.89 | USP2 (0.50) | USP2THRBSMN1; SMN2LMNAKDM4E | |
| SCHEMBL100311 | 0.86 | USP2 (0.48) | USP2THRBCYP3A4SMN1; SMN2LMNA | |
| SCHEMBL9407351 | 0.85 | THRB (0.54) | USP2THRBLMNAKDM4EDUSP3 | |
| SCHEMBL6026201 | 0.84 | USP2 (0.42) | USP2THRBCYP3A4SMN1; SMN2LMNA | |
| SCHEMBL100310 | 0.84 | USP2 (0.47) | USP2THRBCYP3A4SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110117190-A1 | Pharmaceutical Formulations | GLAXO GROUP LIMITED | 2011-05-19 | — | — | US | disclosed |
| EP-2219624-A2 | PHARMACEUTICAL FORMULATIONS | Glaxo Group Limited (GB) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009087483-A2 | PHARMACEUTICAL FORMULATIONS | GLAXO GROUP LIMITED (US) | 2009-07-16 | — | — | WO | disclosed |
| US-20090148518-A1 | Pharmaceutical Formulations | CAPSUGEL BELGIUM NV (BE) | 2009-06-11 | — | — | US | disclosed |