SCHEMBL100311

SCHEMBL100311

OCC(O)COCC(O)CCCC(O)COCC(O)CO

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.48
LMNA P02545 4/20 0.40
ALDH1A1 P00352 1/20 0.40
THRB P10828 1/20 0.39
KDM4E B2RXH2 3/20 0.34
DUSP3 P51452 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
CYP3A4 P08684 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP1A2 P05177 3/20 0.31
AGTR1 P30556 1/20 0.31
PLA2G2C Q5R387 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL100310 0.97 USP2 (0.47) USP2LMNAALDH1A1THRBKDM4E
SCHEMBL7116256 0.90 USP2 (0.45) USP2LMNAALDH1A1THRBKDM4E
SCHEMBL7545745 0.88 USP2 (0.44) USP2LMNAALDH1A1THRBKDM4E
SCHEMBL11913782 0.86 USP2 (0.42) USP2LMNAALDH1A1THRBKDM4E
SCHEMBL2139326 0.86 USP2 (0.47) USP2LMNAALDH1A1THRBKDM4E
SCHEMBL1783854 0.86 USP2 (0.47) USP2LMNAALDH1A1THRBKDM4E
SCHEMBL1638881 0.86 LMNA (0.53) USP2LMNAALDH1A1THRBKDM4E
SCHEMBL30754 0.86 LMNA (0.53) USP2LMNAALDH1A1THRBKDM4E
SCHEMBL9407351 0.84 THRB (0.54) USP2LMNAALDH1A1THRBKDM4E
SCHEMBL9418186 0.84 THRB (0.60) USP2LMNAALDH1A1THRBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8865944-B2 Process for the purification of polyol PFPE derivatives SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2014-10-21 US disclosed
US-8664353-B2 Process for the purification of polyol PFPE derivatives SOLVAY SOLEXIS S.P.A. (IT) 2014-03-04 US disclosed
US-20120055779-A1 Process for the purification of polyol PFPE derivatives SOLVAY SOLEXIS S.P.A. (IT) 2012-03-08 US disclosed
US-20120059144-A1 Process for the purification of polyol PFPE derivatives SOLVAY SOLEXIS S.P.A. (IT) 2012-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120059144-A1 Process for the purification of polyol PFPE derivatives PHYKPL, PKLR, PHOSPHO1 USP2 440/4885LMNA 2429/4885ALDH1A1 1101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.