Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIT1 | Q13231 | 19/20 | 0.49 |
| ▸ | CHIA | Q9BZP6 | 19/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 14/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17838869 | 0.91 | CHIT1 (0.51) | CHIT1CHIAKCNH2MEN1ALDH1A1 | |
| SCHEMBL16826354 | 0.88 | CHIA (0.59) | CHIT1CHIAKCNH2MEN1ALDH1A1 | |
| SCHEMBL17838895 | 0.85 | CHIT1 (0.51) | CHIT1CHIAKCNH2 | |
| SCHEMBL17838860 | 0.84 | CHIT1 (0.45) | CHIT1CHIAKCNH2 | |
| SCHEMBL17838875 | 0.83 | CHIT1 (0.50) | CHIT1CHIAKCNH2 | |
| SCHEMBL21574952 | 0.83 | CHIT1 (0.44) | CHIT1CHIAKCNH2MEN1KMT2A | |
| SCHEMBL21574951 | 0.81 | CHIT1 (0.49) | CHIT1CHIAKCNH2 | |
| SCHEMBL21575058 | 0.81 | CHIT1 (0.54) | CHIT1CHIAKCNH2 | |
| SCHEMBL17838893 | 0.81 | CHIT1 (0.54) | CHIT1CHIAKCNH2 | |
| SCHEMBL17838888 | 0.80 | CHIT1 (0.51) | CHIT1CHIAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233832-B1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | ONCOARENDI THERAPEUTICS SA (PL) | 2019-11-20 | — | — | EP | disclosed |
| EP-3233832-B1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | ONCOARENDI THERAPEUTICS SA (PL) | 2019-11-20 | — | — | EP | disclosed |
| US-20160368894-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | OncoArendi Therapeutics Sp. z o.o. (PL) | 2016-12-22 | — | — | US | disclosed |
| US-20160368894-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | OncoArendi Therapeutics Sp. z o.o. (PL) | 2016-12-22 | — | — | US | disclosed |
| US-20160368894-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | OncoArendi Therapeutics Sp. z o.o. (PL) | 2016-12-22 | — | — | US | disclosed |
| US-9440953-B2 | Substituted amino triazoles useful as acidic mammalian chitinase inhibitors | OncoArendi Therapeutics Sp. z o.o. (PL) | 2016-09-13 | — | — | US | disclosed |
| US-9440953-B2 | Substituted amino triazoles useful as acidic mammalian chitinase inhibitors | OncoArendi Therapeutics Sp. z o.o. (PL) | 2016-09-13 | — | — | US | disclosed |
| US-9440953-B2 | Substituted amino triazoles useful as acidic mammalian chitinase inhibitors | OncoArendi Therapeutics Sp. z o.o. (PL) | 2016-09-13 | — | — | US | disclosed |
| US-20160176843-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | OncoArendi Therapeutics Sp. z o.o. (PL) | 2016-06-23 | — | — | US | disclosed |
| US-20160176843-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | OncoArendi Therapeutics Sp. z o.o. (PL) | 2016-06-23 | — | — | US | disclosed |
| US-20160176843-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | OncoArendi Therapeutics Sp. z o.o. (PL) | 2016-06-23 | — | — | US | disclosed |
| WO-2016099311-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | OncoArendi Therapeutics Sp. z o.o. (PL) | 2016-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160176843-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | CHIA, CHIT1, CMA1 | CHIT1 2/4885CHIA 1/4885KCNH2 4758/4885 |
| US-20160368894-A1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | CHIA, CHIT1, CMA1 | CHIT1 2/4885CHIA 1/4885KCNH2 4758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.