Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIT1 | Q13231 | 19/20 | 0.44 |
| ▸ | CHIA | Q9BZP6 | 19/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 13/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21575086 | 0.92 | CHIT1 (0.47) | CHIT1CHIAKCNH2 | |
| SCHEMBL21574951 | 0.90 | CHIT1 (0.49) | CHIT1CHIAKCNH2 | |
| SCHEMBL17838860 | 0.84 | CHIT1 (0.45) | CHIT1CHIAKCNH2 | |
| SCHEMBL17838853 | 0.83 | CHIT1 (0.49) | CHIT1CHIAKCNH2MEN1KMT2A | |
| SCHEMBL17838868 | 0.81 | CHIT1 (0.48) | CHIT1CHIAKCNH2 | |
| SCHEMBL16826354 | 0.80 | CHIA (0.59) | CHIT1CHIAKCNH2MEN1KMT2A | |
| SCHEMBL17838875 | 0.79 | CHIT1 (0.50) | CHIT1CHIAKCNH2 | |
| SCHEMBL17838869 | 0.78 | CHIT1 (0.51) | CHIT1CHIAKCNH2MEN1KMT2A | |
| SCHEMBL17838895 | 0.78 | CHIT1 (0.51) | CHIT1CHIAKCNH2 | |
| SCHEMBL17838888 | 0.77 | CHIT1 (0.51) | CHIT1CHIAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233832-B1 | SUBSTITUTED AMINO TRIAZOLES USEFUL AS ACIDIC MAMMALIAN CHITINASE INHIBITORS | ONCOARENDI THERAPEUTICS SA (PL) | 2019-11-20 | — | — | EP | disclosed |