Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | FABP3 | P05413 | 5/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octanoic Acid SCHEMBL17453697 | 0.94 | FABP3 (0.60) | DNM1GPR84NFKB1CA1FABP3 | |
| Hexanoate SCHEMBL11176554 | 0.94 | FABP3 (0.60) | DNM1GPR84NFKB1CA1FABP3 | |
| Decanoic Acid SCHEMBL6544079 | 0.94 | FABP3 (0.60) | DNM1GPR84NFKB1CA1FABP3 | |
| Dodecanoate SCHEMBL2953202 | 0.94 | FABP3 (0.60) | DNM1GPR84NFKB1CA1FABP3 | |
| Myristic Acid SCHEMBL20489379 | 0.94 | FABP3 (0.60) | DNM1GPR84NFKB1CA1FABP3 | |
| Hexanoate SCHEMBL17839050 | 0.94 | FABP3 (0.60) | DNM1GPR84NFKB1CA1FABP3 | |
| Decanoic Acid SCHEMBL194214 | 0.94 | FABP3 (0.60) | DNM1GPR84NFKB1CA1FABP3 | |
| Palmitic Acid SCHEMBL28907711 | 0.94 | FABP3 (0.60) | DNM1GPR84NFKB1CA1FABP3 | |
| Octanoic Acid SCHEMBL11573973 | 0.94 | FABP3 (0.60) | DNM1GPR84NFKB1CA1FABP3 | |
| Octanoic Acid SCHEMBL16007959 | 0.92 | DNM1 (0.60) | DNM1GPR84NFKB1CA1FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233872-B1 | QUATERNARY CARBOXYLATE COMPOSITIONS FOR EXTRACTING C1 TO C4 CARBOXYLIC ACIDS FROM AQUEOUS STREAMS | EASTMAN CHEM CO (US) | 2019-10-30 | — | — | EP | disclosed |
| US-9573078-B2 | Quaternary carboxylate compositions for extracting C1 to C4 carboxylic acids from aqueous streams | EASTMAN CHEMICAL COMPANY (US) | 2017-02-21 | — | — | US | disclosed |
| US-20160175737-A1 | Quaternary Carboxylate Compositions for Extracting C1 to C4 Carboxylic Acids from Aqueous Streams | EASTMAN CHEMICAL COMPANY (US) | 2016-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160175737-A1 | Quaternary Carboxylate Compositions for Extracting C1 to C4 Carboxylic Acids from Aqueous Streams | SLC16A3, CA4, SLC16A1 | DNM1 455/4885GPR84 2055/4885NFKB1 1523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.