Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | SQLE | Q14534 | 4/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 3/20 | 0.42 |
| ▸ | FNTB | P49356 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1783919 | 1.00 | KDM1A (0.47) | KDM1ASQLECES1KMT2ACES2 | |
| SCHEMBL11553048 | 0.98 | KDM1A (0.50) | KDM1ASQLECES1KMT2ACES2 | |
| SCHEMBL11553059 | 0.98 | KDM1A (0.50) | KDM1ASQLECES1KMT2ACES2 | |
| SCHEMBL10899279 | 0.94 | KDM1A (0.46) | KDM1ASQLECES1KMT2ACES2 | |
| SCHEMBL10899276 | 0.94 | KDM1A (0.46) | KDM1ASQLECES1KMT2ACES2 | |
| SCHEMBL31181890 | 0.92 | EP300 (0.44) | KDM1ASQLEKMT2AATMPOLB | |
| SCHEMBL28811076 | 0.92 | CES2 (0.46) | CES1KMT2ACES2ATMLSS | |
| SCHEMBL1784245 | 0.86 | KMT2A (0.46) | KDM1ASQLEKMT2AFNTAFNTB | |
| SCHEMBL1784243 | 0.86 | KMT2A (0.46) | KDM1ASQLEKMT2AFNTAFNTB | |
| SCHEMBL31181881 | 0.86 | EP300 (0.46) | KMT2AATMPOLBTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8632792-B2 | Cooling sensation agent composition and sensory stimulation agent composition | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-01-21 | — | — | US | disclosed |
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-05-19 | — | — | US | disclosed |
| WO-2009123355-A2 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-08 | — | — | WO | disclosed |
| EP-0175427-A1 | Synthesis of dioxabicyclo[3.2.1]octanes | ORTHO PHARMACEUTICAL CORPORATION (US) | 1986-03-26 | — | — | EP | disclosed |
| EP-0045631-A2 | Synthesis of dioxabicyclo(3.2.1)octanes and oxepanes | ORTHO PHARMACEUTICAL CORPORATION (US) | 1982-02-10 | — | — | EP | disclosed |
| US-4276216-A | Synthesis of dioxabicyclo[3.2.1]octanes and oxepanes | ORTHO PHARMACEUTICAL CORPORATION (US) | 1981-06-30 | — | — | US | disclosed |
| US-4011335-A | INSECTICIDES, HORMONE INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 1977-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TRPA1, HRH1, HRH2 | KDM1A 2902/4885SQLE 1861/4885CES1 1998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.