SCHEMBL178423

SCHEMBL178423

CNCc1cccs1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6121921 0.98
SCHEMBL3159042 0.80 LMNA (0.68)
SCHEMBL13123453 0.78
Hydrochloric Acid SCHEMBL6122085 0.78 KMT2A (0.69)
SCHEMBL2719543 0.77
SCHEMBL680547 0.77
SCHEMBL559559 0.76 TAAR1 (0.56)
SCHEMBL11032881 0.76
Dimethylamine SCHEMBL4430498 0.76 MEN1 (0.52)
SCHEMBL7086135 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 373 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4669479-B2 2011-04-13 JP claimed
EP-1699778-B1 (4-PHENYLPIPERAZIN-1-YL)ACYLPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND APPLICATION OF SAME IN THERAPEUTICS SANOFI AVENTIS (FR) 2010-07-14 EP claimed
EP-2079699-A1 QUINOLINE DERIVATIVES Envivo Pharmaceuticals, Inc. (US) 2009-07-22 EP claimed
US-7423039-B2 (4-phenylpiperazin-1-yl)acylpiperidine derivatives, preparation thereof and application of same in therapeutics SANOFI-AVENTIS (FR) 2008-09-09 US claimed
US-20080200454-A1 CARBON-LINKED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S SUNESIS PHARMACEUTICALS, INC. 2008-08-21 US claimed
WO-2008100618-A2 CARBON-LINKED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S SUNESIS PHARMACEUTICALS, INC. (US) 2008-08-21 WO claimed
WO-2008014602-A1 QUINOLINE DERIVATIVES ENVIVO PHARMACEUTICALS, INC. (US) 2008-02-07 WO claimed
JP-2007512385-A 2007-05-17 JP claimed
US-20070021609-A1 4-PHENYLPIPERAZIN-1-YL)ACYLPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND APPLICATION OF SAME IN THERAPEUTICS SANOFI-AVENTIS (FR) 2007-01-25 US claimed
EP-1699778-A1 (4-PHENYLPIPERAZIN-1-YL)ACYLPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND APPLICATION OF SAME IN THERAPEUTICS Sanofi-Aventis (FR) 2006-09-13 EP claimed
WO-2005054227-A1 (4-PHENYLPIPERAZIN-1-YL)ACYLPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND APPLICATION OF SAME IN THERAPEUTICS SANOFI-AVENTIS (FR) 2005-06-16 WO claimed
WO-2026099602-A1 DOMINO KNOEVENAGEL-INTRAMOLECULAR CYCLIZATION REACTIONS USING FIVE-MEMBERED AROMATIC HETEROCYCLES WITH ONE HETEROATOM AS A DIENE OR DIENOPHILE DEBRECENI EGYETEM (HU) 2026-05-15 WO disclosed
CN-121673214-A Synthetic method of isoindolone 南京工业大学 2026-03-17 CN disclosed
EP-4703355-A1 FLUORINE-CONTAINING ISOXAZOLONE COMPOUND AND PRODUCTION METHOD FOR SAME Unimatec Co., Ltd. (JP) 2026-03-04 EP disclosed
CN-121378099-A Application of isoindolone compound 南京工业大学 2026-01-23 CN disclosed
EP-0465254-A1 Fused thiophene compounds and uses thereof YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1992-01-08 EP disclosed
US-4876271-A GLAUCOMA MERCK & CO., INC. (US) 1989-10-24 US disclosed
US-4806562-A Substituted thieno[2,3-b]thiophene-2-sulfonamides as antiglaucoma agents MERCK & CO., INC. (US) 1989-02-21 US disclosed
US-4751231-A Substituted thieno[2,3-b]pyrrole-5-sulfonamides as antiglaucoma agents MERCK & CO., INC. (US) 1988-06-14 US disclosed
US-4239769-A ANTISECRETORY AGENT; GASTRIC JUICE ALLEN & HANBURYS LIMITED (GB) 1980-12-16 US disclosed