Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6122085 | 0.97 | KMT2A (0.69) | LMNAPOLBKMT2AMEN1L3MBTL1 | |
| SCHEMBL22305112 | 0.89 | LMNA (0.68) | LMNAPOLBKMT2AMEN1L3MBTL1 | |
| SCHEMBL3625005 | 0.87 | LMNA (0.71) | LMNAPOLBKMT2AMEN1L3MBTL1 | |
| SCHEMBL2719543 | 0.86 | — | — | |
| SCHEMBL4524507 | 0.86 | — | — | |
| SCHEMBL13922748 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL28571763 | 0.84 | KMT2A (0.66) | LMNAPOLBKMT2AMEN1L3MBTL1 | |
| SCHEMBL10962630 | 0.84 | MAOB (0.59) | LMNAPOLBKMT2AMEN1L3MBTL1 | |
| SCHEMBL23736016 | 0.84 | LMNA (0.62) | LMNAPOLBKMT2AMEN1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL6127562 | 0.83 | MAOB (0.72) | LMNAPOLBKMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700628-B2 | Aromatic ether derivatives useful as thrombin inhibitors | ELI LILLY AND COMPANY (US) | 2010-04-20 | — | — | US | claimed |
| EP-1817287-B1 | AROMATIC ETHER DERIVATIVES USEFUL AS THROMBIN INHIBITORS | LILLY CO ELI (US) | 2010-02-10 | — | — | EP | claimed |
| US-7615659-B2 | Preparing a palladium(0) compound by the reaction of a palladium compound with a silicone containing compound in the presence of a base; palladium(0) compounds are suitable as homogeneous catalysts, or as precursors for preparing homogeneous catalysts; storage stability | UMICORE AG & CO. KG (DE) | 2009-11-10 | — | — | US | claimed |
| US-20090227566-A1 | AROMATIC ETHER DERIVATIVES USEFUL AS THROMBIN INHIBITORS | ELI LILLY AND COMPANY | 2009-09-10 | — | — | US | claimed |
| EP-1558621-B1 | METHODS FOR THE PREPARATION OF COMPOUNDS CONTAINING PALLADIUM (0) | UMICORE AG & CO KG (DE) | 2008-01-23 | — | — | EP | claimed |
| EP-1817287-A1 | AROMATIC ETHER DERIVATIVES USEFUL AS THROMBIN INHIBITORS | Eli Lilly and Company (US) | 2007-08-15 | — | — | EP | claimed |
| WO-2006057845-A1 | AROMATIC ETHER DERIVATIVES USEFUL AS THROMBIN INHIBITORS | ELI LILLY AND COMPANY (US) | 2006-06-01 | — | — | WO | claimed |
| US-20060106239-A1 | Method for the production of compounds containing palladium(0) | UMICORE AG & CO. KG (DE) | 2006-05-18 | — | — | US | claimed |
| EP-1558621-A2 | METHOD FOR THE PRODUCTION OF COMPOUNDS CONTAINING PALLADIUM (0) | Umicore AG & Co. KG (DE) | 2005-08-03 | — | — | EP | claimed |
| US-20040142999-A1 | Novel compounds and compositions as cathepsin inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2004-07-22 | — | — | US | claimed |
| WO-2004039819-A2 | METHOD FOR THE PRODUCTION OF COMPOUNDS CONTAINING PALLADIUM (0) | UMICORE AG & CO. KG (DE) | 2004-05-13 | — | — | WO | claimed |
| EP-1397340-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS CATHEPSIN S INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2004-03-17 | — | — | EP | claimed |
| US-6686495-B2 | IN PRESENCE OF PALLADIUM CATALYST; USEFUL IN PRODUCING CHEMICAL INTERMEDIATES FOR PHARMACEUTICALS, OPTICAL BRIGHTENING AGENTS AND AGROCHEMICALS | OMG AG & CO KG (DE) | 2004-02-03 | — | — | US | claimed |
| WO-2002098850-A2 | CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS CATHEPSIN S INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-12-12 | — | — | WO | claimed |
| US-20020107426-A1 | Process for the preparation of mono-, bi- or poly- functional biaryls | UMICORE AG & CO. KG (DE) | 2002-08-08 | — | — | US | claimed |
| EP-1199292-A1 | Process for the production of mono-, bi- or polyfunctional biaryls | OMG AG & Co. KG (DE) | 2002-04-24 | — | — | EP | claimed |
| EP-4384516-A1 | AMINOARYL-INTEGRIN AGONISTS COMPOUNDS | Texas Heart Institute (US) | 2024-06-19 | — | — | EP | disclosed |
| CN-117916237-A | Amino aryl integrin agonist compounds | 德克萨斯心脏研究所 | 2024-04-19 | — | — | CN | disclosed |
| US-5321047-A | Antidepressant | JOHN WYETH & BROTHER, LIMITED (GB) | 1994-06-14 | — | — | US | disclosed |
| EP-0345068-A2 | Agonist of gamma-aminobutyric acid | JOHN WYETH & BROTHER LIMITED (GB) | 1989-12-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106239-A1 | Method for the production of compounds containing palladium(0) | RPS19, SCO2, MMS19 | LMNA 4664/4885POLB 200/4885KMT2A 2029/4885 |
| US-20040142999-A1 | Novel compounds and compositions as cathepsin inhibitors | CTSS, CTSB, CTSE | LMNA 1707/4885POLB 2141/4885KMT2A 4623/4885 |
| US-20020107426-A1 | Process for the preparation of mono-, bi- or poly- functional biaryls | CYP4F3, CYP4F2, CYP2F1 | LMNA 1670/4885POLB 113/4885KMT2A 2368/4885 |
| US-20090227566-A1 | AROMATIC ETHER DERIVATIVES USEFUL AS THROMBIN INHIBITORS | TFPI, F2, F11 | LMNA 939/4885POLB 4133/4885KMT2A 2775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.