Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 16/20 | 0.54 |
| ▸ | F10 | P00742 | 2/20 | 0.45 |
| ▸ | HTR3A | P46098 | 5/20 | 0.44 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.41 |
| ▸ | DHPS | P49366 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8306899 | 0.75 | CHRNA7 (0.58) | CHRNA7F10HTR3A | |
| SCHEMBL17842890 | 0.72 | CHRNA7 (0.63) | CHRNA7HTR3A | |
| SCHEMBL19739754 | 0.70 | CHRNA7 (1.00) | CHRNA7HTR3A | |
| SCHEMBL17843029 | 0.70 | CHRNA7 (1.00) | CHRNA7HTR3A | |
| SCHEMBL19739695 | 0.70 | CHRNA7 (1.00) | CHRNA7HTR3A | |
| SCHEMBL18264044 | 0.70 | CHRNA1 (0.59) | CHRNA7F10 | |
| SCHEMBL18264045 | 0.70 | CHRNA1 (0.59) | CHRNA7F10 | |
| SCHEMBL11173925 | 0.70 | DHPS (0.52) | CHRNA7F10PRSS12DHPS | |
| Hydrochloric Acid SCHEMBL19741138 | 0.70 | CHRNA7 (0.98) | CHRNA7HTR3A | |
| SCHEMBL19739725 | 0.70 | CHRNA7 (1.00) | CHRNA7HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233087-A1 | GEMINAL SUBSTITUTED QUINUCLIDINE AMIDE COMPOUNDS AS AGONISTS OF ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTORS | Axovant Sciences GmbH (DE) | 2017-10-25 | — | — | EP | claimed |
| WO-2016100184-A1 | GEMINAL SUBSTITUTED QUINUCLIDINE AMIDE COMPOUNDS AS AGONISTS OF ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTORS | FORUM PHARMACEUTICALS, INC. (US) | 2016-06-23 | — | — | WO | claimed |