Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 4/20 | 0.58 |
| ▸ | F10 | P00742 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18264045 | 0.86 | CHRNA1 (0.59) | CHRNA7F10 | |
| SCHEMBL18264044 | 0.86 | CHRNA1 (0.59) | CHRNA7F10 | |
| SCHEMBL395370 | 0.82 | HDAC3 (0.60) | CHRNA7RAB9ANPC1MEN1KMT2A | |
| SCHEMBL18264041 | 0.76 | CHRNA1 (0.59) | CHRNA7F10RAB9AMEN1KMT2A | |
| SCHEMBL18264043 | 0.76 | CHRNA1 (0.59) | CHRNA7F10RAB9AMEN1KMT2A | |
| SCHEMBL11173925 | 0.76 | DHPS (0.52) | CHRNA7F10KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL12507834 | 0.75 | NPC1 (0.69) | F10RAB9ANPC1L3MBTL1HPGD | |
| SCHEMBL13709578 | 0.75 | LMNA (0.58) | RAB9ANPC1THRBHPGDALDH1A1 | |
| SCHEMBL17843152 | 0.75 | CHRNA7 (0.54) | CHRNA7F10HTR3A | |
| SCHEMBL19902484 | 0.74 | CHRNA7 (0.46) | CHRNA7F10RAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004082687-A1 | LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-09-30 | — | — | WO | disclosed |