SCHEMBL1784333

SCHEMBL1784333

CCCCCC/C=C/C(C)C=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.54
TRPV1 Q8NER1 2/20 0.54
TSHR P16473 2/20 0.48
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
CYP3A4 P08684 1/20 0.47
ALDH1A1 P00352 2/20 0.45
ASAH2 Q9NR71 1/20 0.45
MAPT P10636 4/20 0.44
GMNN O75496 3/20 0.44
LMNA P02545 3/20 0.44
POLB P06746 3/20 0.44
BLM P54132 3/20 0.44
GLA P06280 2/20 0.44
THRB P10828 2/20 0.44
CETP P11597 2/20 0.44
MAPK1 P28482 2/20 0.44
CXCR5 P32302 2/20 0.44
CCR6 P51684 2/20 0.44
UBE2N P61088 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1784335 1.00 FAAH (0.54) FAAHTRPV1TSHRMEN1KMT2A
SCHEMBL1782966 0.98 FAAH (0.50) FAAHTRPV1TSHRMEN1KMT2A
SCHEMBL1782969 0.98 FAAH (0.50) FAAHTRPV1TSHRMEN1KMT2A
SCHEMBL1783383 0.91 TSHR (0.44) FAAHTRPV1TSHRMEN1KMT2A
SCHEMBL1783382 0.91 TSHR (0.44) FAAHTRPV1TSHRMEN1KMT2A
SCHEMBL29083515 0.85 MEN1 (0.52) FAAHTRPV1MEN1KMT2ACYP3A4
SCHEMBL1781361 0.82
SCHEMBL5613640 0.78 MEN1 (0.53) FAAHTRPV1MEN1KMT2ACYP3A4
SCHEMBL5613321 0.78 MEN1 (0.53) FAAHTRPV1MEN1KMT2ACYP3A4
SCHEMBL5613219 0.78 MEN1 (0.53) FAAHTRPV1MEN1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8632792-B2 Cooling sensation agent composition and sensory stimulation agent composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-01-21 US disclosed
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-05-19 US disclosed
WO-2009123355-A2 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TRPA1, HRH1, HRH2 FAAH 94/4885TRPV1 8/4885TSHR 2479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.