Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PI4KA | P42356 | 1/20 | 0.48 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.48 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.48 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17861288 | 0.81 | ALDH1A1 (0.54) | MAPTALDH1A1PI4KAPI4K2BPI4K2A | |
| SCHEMBL10902105 | 0.80 | CYP3A4 (0.66) | MAPTALDH1A1HTTCYP1A2CYP2C9 | |
| SCHEMBL17844061 | 0.79 | ALDH1A1 (0.43) | MAPTALDH1A1SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL5387033 | 0.79 | MKNK1 (0.46) | MAPTALDH1A1SMN1; SMN2HTTFGFR1 | |
| SCHEMBL8511275 | 0.79 | HTT (0.45) | MAPTALDH1A1SMN1; SMN2PI4KAPI4K2B | |
| SCHEMBL6598961 | 0.79 | CYP1A2 (0.47) | MAPTALDH1A1SMN1; SMN2PI4KAPI4K2B | |
| SCHEMBL22309911 | 0.78 | CYP1A2 (0.44) | MAPTALDH1A1SMN1; SMN2PI4KAPI4K2B | |
| SCHEMBL11771718 | 0.77 | KDR (0.49) | ALDH1A1SMN1; SMN2HTTCYP1A2CYP2C9 | |
| SCHEMBL17596915 | 0.77 | HTT (0.41) | MAPTALDH1A1SMN1; SMN2PI4KAPI4K2B | |
| SCHEMBL11382721 | 0.76 | CYP1A2 (0.49) | MAPTALDH1A1HTTCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117377668-A | Inhalant formulations of PGDH inhibitors and methods of use thereof | 迈欧伏特治疗公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-115335043-A | PGDH inhibitors and methods of making and using | 迈欧伏特治疗公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-107105657-B | Molecules having pesticidal utility, and intermediates, compositions, and methods related thereto | 美国陶氏益农公司 | 2020-03-03 | — | — | CN | disclosed |
| EP-3232788-B1 | TRIAZOLES DERIVATIVES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-06-12 | — | — | EP | disclosed |
| EP-3232788-B1 | TRIAZOLES DERIVATIVES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-06-12 | — | — | EP | disclosed |
| US-20170360045-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | CORTEVA AGRISCIENCE LLC | 2017-12-21 | — | — | US | disclosed |
| US-20170360045-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | CORTEVA AGRISCIENCE LLC | 2017-12-21 | — | — | US | disclosed |
| EP-3232788-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | Dow AgroSciences LLC (US) | 2017-10-25 | — | — | EP | disclosed |
| CN-107105657-A | Molecule and relative intermediate, composition and method with desinsection effectiveness | 美国陶氏益农公司 | 2017-08-29 | — | — | CN | disclosed |
| WO-2016099929-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2016-06-23 | — | — | WO | disclosed |
| WO-2016099929-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2016-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170360045-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | ACHE, DDT, MSMO1 | MAPT 3341/4885ALDH1A1 448/4885SMN1; SMN2 3681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.