SCHEMBL17844313

SCHEMBL17844313

c1ccc(-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3ccccc3N(c3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
TDP1 Q9NUW8 3/20 0.46
CYP1A2 P05177 2/20 0.46
CYP3A4 P08684 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
MAPT P10636 2/20 0.46
KDM4E B2RXH2 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
MGLL Q99685 1/20 0.41
TAAR1 Q96RJ0 3/20 0.40
MAPK1 P28482 1/20 0.40
HSD17B10 Q99714 1/20 0.40
MMP3 P08254 1/20 0.40
BCL2L1 Q07817 1/20 0.40
MEN1 O00255 1/20 0.39
CRHBP P24387 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7247455 0.97 ALDH1A1 (0.48) ALDH1A1TDP1CYP1A2CYP3A4L3MBTL1
SCHEMBL21168411 0.89 MGLL (0.39) ALDH1A1TDP1CYP1A2CYP3A4L3MBTL1
SCHEMBL21364922 0.89 ALDH1A1 (0.41) ALDH1A1TDP1CYP1A2CYP3A4L3MBTL1
SCHEMBL21364924 0.89 ALDH1A1 (0.41) ALDH1A1TDP1CYP1A2CYP3A4L3MBTL1
SCHEMBL21168448 0.89 ALDH1A1 (0.41) ALDH1A1TDP1CYP1A2CYP3A4L3MBTL1
SCHEMBL21168443 0.89 ALDH1A1 (0.41) ALDH1A1TDP1CYP1A2CYP3A4L3MBTL1
SCHEMBL24755117 0.87 ALDH1A1 (0.59) ALDH1A1TDP1CYP1A2CYP3A4L3MBTL1
SCHEMBL22017677 0.87 ALDH1A1 (0.59) ALDH1A1TDP1CYP1A2CYP3A4L3MBTL1
SCHEMBL24467954 0.87 ALDH1A1 (0.59) ALDH1A1TDP1CYP1A2CYP3A4L3MBTL1
SCHEMBL22972387 0.87 ALDH1A1 (0.59) ALDH1A1TDP1CYP1A2CYP3A4L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016097983-A1 1-FUNCTIONALIZED DIBENZOFURANS AND DIBENZOTHIOPHENES FOR ORGANIC LIGHT EMITTING DIODES (OLEDS) IDEMITSU KOSAN CO., LTD. (JP) 2016-06-23 WO disclosed